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Cell type vulnerability in Alzheimers Disease (SEA-AD transcriptomic data)

analysis Created: 2026-04-10T17:46:29 By: crosslink-v2 Quality: 50% ✓ SciDEX ID: analysis-SDA-2026-04-03-gap-seaad-v4-202

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Linked Artifacts (229)

derives_from📓Cell type vulnerability in Alzheimers Disease (SEA-AD transc100%

produces📓Cell type vulnerability in Alzheimers Disease (SEA-AD transc100%

related📖ACSL4 Gene - Acyl-CoA Synthetase Long Chain Family Member 470%

related📖ai-tool-celltypist70%

related📖ai-tool-scgpt70%

related📖Disease-Associated Microglia (DAM)70%

related📖Microglia in Alzheimer's Disease Neurodegeneration70%

related📖Microglia in Batten Disease70%

related📖Microglia in Huntington's Disease70%

related📖Microglia in Chronic Neuroinflammation70%

related📖Microglia in Nasu-Hakola Disease70%

related📖Microglia in Alzheimer's Disease Neurodegeneration70%

related📖Microglia in Neuroinflammation70%

related📖Microglia in Parkinson Disease70%

related📖Microglia in Rasmussen Encephalitis70%

related📖Microglia State Index70%

related📖Microglia in Synapse Pruning70%

related📖Microglia in Parkinson's Disease Substantia Nigra70%

related📖Microglia70%

related📖Microglia in Neurodegeneration70%

related📖Microglia-Targeted Nanoparticles for CNS Delivery70%

related📖Microglia-State Editing via TREM2-LXR Pulse Program70%

related📖Microglia Activation Mechanism70%

related📖Microglia in Corticobasal Degeneration70%

related📖Microglia in Frontotemporal Dementia Progression70%

related📖Microglia and neuroinflammation in Alzheimer's Disease70%

related📖Microglia-Neuron Metabolic Cross-Talk in Neurodegeneration70%

related📖Microglia Depletion and Repopulation Therapy70%

related📖Microglia Modulation Therapies70%

related📖Microglia Modulation Therapy for Neurodegeneration70%

related📖Astrocyte-Derived Exosomal mRNA Reference Genes for Alzheime70%

related📖Astrocyte Precursor Cells70%

related📖Astrocyte-Targeted Parkinson's Disease Therapies70%

related📖Astrocyte-Targeted Parkinson's Disease Therapy Companie70%

related📖BICCN Human Brain Cell Atlas70%

related📖BrainSpan Atlas70%

related📖nih-blueprint-neuroimaging70%

related📖oasis70%

related📖AAIC 2026 ISTAART Sessions70%

related📖Conference Index70%

related📖Astrocyte Ferritin Iron Metabolism Dysfunction in Parkinson&70%

related📖astrocyte-neuron-metabolic-coupling-parkinsons70%

related📖Mixed Pathology Effects on Parkinson's Disease Progress70%

related📖Protein Aggregation Kinetic Validation Results70%

related📖Astrocyte-Neuron Metabolic Coupling Hypothesis in Parkinson&70%

related📖Astrocyte-to-Neuron Reprogramming Therapy70%

related📖Astrocyte Glutamate-Buffer Rescue: EAAT2 Transcription Reboo70%

related📖Astrocyte Glutamate-Buffer Rescue with EAAT2 Transcription R70%

related📖Astrocyte Therapeutics for Neurodegeneration: Investment Ana70%

related📖Astrocyte Dysfunction in Parkinson's Disease70%

related📖Astrocyte Iron Metabolism and Alpha-Synuclein Pathology in P70%

related📖Astrocyte Metabolic Enhancement Therapy for PD70%

related📖Astrocyte-Mediated Neuroinflammation70%

related📖Astrocyte-Neuron Metabolic Coupling Pathway70%

related📖Astrocyte Reactivity Mechanism70%

related📖Astrocyte Reactivity in 4R-Tauopathies70%

related📖Astrocyte Senescence Pathway in Neurodegeneration70%

related📖Invicro70%

related📖Astrocyte Metabolic Modulation Therapy for Neurodegeneration70%

related📖astrocyte-modulation-therapy70%

related📖Neuron-Specific Enolase (NSE) - Biomarker70%

related📖Mitochondrial Dynamics Dysregulation in Neurodegeneration70%

related📖NeuRon Therapeutics70%

related📖Mitochondrial Quality Control in Neurons68%

related📖Mitochondrial Quality Control68%

related📖ACSL4 Gene - Acyl-CoA Synthetase Long Chain Family Member 463%

related📖ai-tool-celltypist63%

related📖ai-tool-scgpt63%

related📖Disease-Associated Microglia (DAM)63%

related📖Microglia in Alzheimer's Disease Neurodegeneration63%

related📖Microglia in Batten Disease63%

related📖Microglia in Huntington's Disease63%

related📖Microglia in Chronic Neuroinflammation63%

related📖Microglia in Nasu-Hakola Disease63%

related📖Microglia in Alzheimer's Disease Neurodegeneration63%

related📖Microglia in Neuroinflammation63%

related📖Microglia in Parkinson Disease63%

related📖Microglia in Rasmussen Encephalitis63%

related📖Microglia State Index63%

related📖Microglia in Synapse Pruning63%

related📖Microglia in Parkinson's Disease Substantia Nigra63%

related📖Microglia in Neurodegeneration63%

related📖Microglia-Targeted Nanoparticles for CNS Delivery63%

related📖Microglia-State Editing via TREM2-LXR Pulse Program63%

related📖Microglia Activation Mechanism63%

related📖Microglia in Corticobasal Degeneration63%

related📖Microglia in Frontotemporal Dementia Progression63%

related📖Microglia and neuroinflammation in Alzheimer's Disease63%

related📖Microglia-Neuron Metabolic Cross-Talk in Neurodegeneration63%

related📖Microglia Depletion and Repopulation Therapy63%

related📖Microglia Modulation Therapies63%

related📖Microglia Modulation Therapy for Neurodegeneration63%

related📖Astrocyte-Derived Exosomal mRNA Reference Genes for Alzheime63%

related📖Astrocyte Precursor Cells63%

related📖Astrocyte-Targeted Parkinson's Disease Therapies63%

related📖Astrocyte-Targeted Parkinson's Disease Therapy Companie63%

related📖BICCN Human Brain Cell Atlas63%

related📖BrainSpan Atlas63%

related📖nih-blueprint-neuroimaging63%

related📖oasis63%

related📖AAIC 2026 ISTAART Sessions63%

related📖Conference Index63%

related📖Astrocyte Ferritin Iron Metabolism Dysfunction in Parkinson&63%

related📖astrocyte-neuron-metabolic-coupling-parkinsons63%

related📖Mixed Pathology Effects on Parkinson's Disease Progress63%

related📖Protein Aggregation Kinetic Validation Results63%

related📖Astrocyte-Neuron Metabolic Coupling Hypothesis in Parkinson&63%

related📖Astrocyte-to-Neuron Reprogramming Therapy63%

related📖Astrocyte Glutamate-Buffer Rescue: EAAT2 Transcription Reboo63%

related📖Astrocyte Glutamate-Buffer Rescue with EAAT2 Transcription R63%

related📖Astrocyte Therapeutics for Neurodegeneration: Investment Ana63%

related📖Astrocyte Dysfunction in Parkinson's Disease63%

related📖Astrocyte Iron Metabolism and Alpha-Synuclein Pathology in P63%

related📖Astrocyte Metabolic Enhancement Therapy for PD63%

related📖Astrocyte-Mediated Neuroinflammation63%

related📖Astrocyte-Neuron Metabolic Coupling Pathway63%

related📖Astrocyte Reactivity Mechanism63%

related📖Astrocyte Reactivity in 4R-Tauopathies63%

related📖Astrocyte Senescence Pathway in Neurodegeneration63%

related📖Invicro63%

related📖Astrocyte Metabolic Modulation Therapy for Neurodegeneration63%

related📖astrocyte-modulation-therapy63%

related📖Neuron-Specific Enolase (NSE) - Biomarker63%

related📖Mitochondrial Dynamics Dysregulation in Neurodegeneration63%

related📖NeuRon Therapeutics63%

related📖Mitochondrial Quality Control in Neurons61%

related📖Mitochondrial Quality Control61%

mentions📖Seattle Alzheimer's Disease Brain Cell Atlas (SEA-AD)60%

mentions📖Allen Brain Cell Atlas60%

mentions📖Astrocytes60%

mentions📖cell-types60%

mentions📖mechanisms60%

mentions📖Microglia60%

mentions📖Oligodendrocytes60%

mentions📖entities-oligodendrocytes60%

related📖Seattle Alzheimer's Disease Brain Cell Atlas (SEA-AD)54%

related📖Allen Brain Cell Atlas54%

related📖Astrocytes54%

related📖cell-types54%

related📖mechanisms54%

related📖Microglia54%

related📖Oligodendrocytes54%

related📖entities-oligodendrocytes54%

mentions📖Beta-Propeller Protein-Associated Neurodegeneration (BPAN)50%

mentions📖China Neurodegeneration Epidemiology50%

mentions📖DALY Methodology — Neurodegeneration50%

mentions📖Disease Progression & Staging in Neurodegeneration50%

mentions📖Economic Burden — Neurodegeneration50%

mentions📖European Neurodegeneration Epidemiology50%

mentions📖Familial vs Sporadic Neurodegeneration Comparison50%

mentions📖Global Neurodegeneration Epidemiology50%

mentions📖India Neurodegeneration Epidemiology50%

mentions📖Japan Neurodegeneration Epidemiology50%

mentions📖Manganese-Related Neurodegeneration (Manganism)50%

mentions📖mitochondrial-dysfunction-neurodegeneration-comparison50%

mentions📖Mitochondrial Diseases and Neurodegeneration Comparison Matr50%

mentions📖Mitochondrial Membrane Protein-Associated Neurodegeneration 50%

mentions📖Neurodegeneration with Brain Iron Accumulation (NBIA)50%

mentions📖Neurodegeneration50%

mentions📖Potential Impact Measures — Neurodegeneration50%

mentions📖Pantothenate Kinase-Associated Neurodegeneration (PKAN)50%

mentions📖PLA2G6-Associated Neurodegeneration (PLAN)50%

mentions📖Sleep Disorders in Neurodegeneration50%

mentions📖US Neurodegeneration Epidemiology50%

related📖SIRT3 - Sirtuin 340%

related📖SLC16A1 — Solute Carrier Family 16 Member 1 (Monocarboxylate40%

related📖CLDN5 — Claudin-540%

related📖Glial Fibrillary Acidic Protein (GFAP)40%

related📖entities-gfap40%

related📖GFAP (Glial Fibrillary Acidic Protein Gene)40%

related📖GFAP (Glial Fibrillary Acidic Protein)40%

related📖GPX4 Gene - Glutathione Peroxidase 440%

related📖GPX4 (Glutathione Peroxidase 4)40%

related📖HMGCR — 3-Hydroxy-3-Methylglutaryl-CoA Reductase40%

related📖MMP9 Gene40%

related📖MMP9 Protein40%

related📖PDGFRB — Platelet Derived Growth Factor Receptor Beta40%

related📖PPARGC1A Gene40%

related📖PVALB Gene - Parvalbumin40%

related📖SREBF2 — Sterol Regulatory Element Binding Transcription Fac40%

related📖TFAM Gene40%

related📖TFRC40%

related📖sTREM2 (Soluble TREM2) - Biomarker40%

related📖TREM2 Protein (Triggering Receptor Expressed on Myeloid Cell40%

related📖TREM2 — Triggering Receptor Expressed on Myeloid Cells 240%

related📖trem2-alpha-synuclein-clearance-parkinsons40%

related📖TREM2 Mechanism Hub40%

related📖TREM2 Protein40%

related📖ai-tool-alibaba-tongyi-qianwen-bio40%

related📖ai-tool-bioframe40%

related📖ai-tool-biorxiv-literature-agent40%

related📖ai-tool-nucleus-dnastack40%

related📖ai-tool-openai-codex-biology40%

related📖ai-tools-inference-bio40%

related📖Neurodegeneration40%

related📖Ferroptosis-Sensitive Neurons40%

related📖Ferroptosis40%

related📖Ferroptosis Validation in Parkinson's Disease40%

related📖Ferroptosis Hypothesis in Parkinson's Disease40%

related📖Ferroptosis Inhibition Therapy40%

related📖Ferroptosis Modulation Investment Landscape40%

related📖Ferroptosis in Neurodegeneration40%

related📖ferroptosis-4r-tauopathies40%

related📖Ferroptosis in Alzheimer's Disease40%

related📖Ferroptosis Pathway in Alzheimer's Disease40%

related📖Ferroptosis in Alzheimer's Disease40%

related📖Ferroptosis and Lipid Peroxidation in 4R-Tauopathies40%

related📖Ferroptosis in Neurodegeneration40%

related📖Ferroptosis Pathway in Neurodegeneration40%

related📖Ferroptosis in Parkinson's Disease40%

related📖Ferroptosis Pathway in Neurodegeneration40%

related📖Ferroptosis Inhibitors40%

related📖Ferroptosis Modulation Therapy40%

related📖Ferroptosis Therapy for Parkinson's Disease40%

related📖C3 — Complement Component 340%

related📖PARP1 Gene40%

related📖PARP1 (Poly(ADP-Ribose) Polymerase 1)40%

related📖cell-types-pink1-deficient-dopamine-neurons30%

related📖PINK1 (PTEN-Induced Kinase 1)30%

related📖PINK1 — PTEN Induced Kinase 130%

related📖PINK1 Protein30%

related📖PINK130%