🧫

GWAS of composite biomarker score

experiment Created: 2026-04-11 00:50:30 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-2267dce9-5cf9-4e2f-a543-e
🧫 Experiment Protocol Genetic Association
🧫 View Full Experiment Page →
Related Entities
PPP4R2, APOE
Metadata
experiment_typegenetic_association
protocolCreation of composite score from multiple biomarkers, genome-wide association analysis using same genotyping and QC procedures
expected_outcomesIdentification of genetic loci with pleiotropic effects across multiple AD biomarkers
success_criteriagenome-wide significance (p < 5×10^-8)
sample_size1,972
statistical_methodscomposite score generation, genome-wide association analysis
p_valueNone
effect_sizeNone
extracted_at2026-04-10T17:50:30.815001
source_pmid41804841
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-11T00:50:30.923873'}
Linked Artifacts (76)
mentions📖APOE-Expressing Astrocytes80%
mentions📖APOE Genotyping for Neurodegenerative Disease Risk Assessmen80%
mentions📖apoe80%
mentions📖APOE contributes to Alzheimer's disease by regulating b80%
mentions📖hypotheses-apoe-contributes-alzheimers-disease-regulat80%
mentions📖APOE Lipid Dysregulation Causal Chain in AD80%
mentions📖APOE Lipid Metabolism Pathway in Alzheimer's Disease80%
mentions📖ApoE (Apolipoprotein E)80%
mentions📖apoe-genotype-guided-prevention80%
related📖APOE-Expressing Astrocytes72%
related📖APOE Genotyping for Neurodegenerative Disease Risk Assessmen72%
related📖apoe72%
related📖APOE contributes to Alzheimer's disease by regulating b72%
related📖hypotheses-apoe-contributes-alzheimers-disease-regulat72%
related📖APOE Lipid Dysregulation Causal Chain in AD72%
related📖APOE Lipid Metabolism Pathway in Alzheimer's Disease72%
related📖ApoE (Apolipoprotein E)72%
related📖apoe-genotype-guided-prevention72%
mentions📖GFAP in Alzheimer's Disease70%
mentions📖gfap-biomarker-ad70%
mentions📖GFAP (Glial Fibrillary Acidic Protein) - Biomarker70%
mentions📖GFAP (Glial Fibrillary Acidic Protein) - Diagnostic Marker70%
mentions📖entities-gfap70%
mentions📖GFAP (Glial Fibrillary Acidic Protein Gene)70%
mentions📖GFAP-Guided Astrocyte Modulation Therapy70%
mentions📖GFAP (Glial Fibrillary Acidic Protein)70%
mentions📖GFAP Protein70%
mentions📖GWAS Findings Hub70%
mentions📖GWAS Findings Hub: Alzheimer's and Parkinson's Dis70%
related📖GFAP in Alzheimer's Disease63%
related📖gfap-biomarker-ad63%
related📖GFAP (Glial Fibrillary Acidic Protein) - Biomarker63%
related📖GFAP (Glial Fibrillary Acidic Protein) - Diagnostic Marker63%
related📖entities-gfap63%
related📖GFAP (Glial Fibrillary Acidic Protein Gene)63%
related📖GFAP-Guided Astrocyte Modulation Therapy63%
related📖GFAP (Glial Fibrillary Acidic Protein)63%
related📖GFAP Protein63%
related📖GWAS Findings Hub63%
related📖GWAS Findings Hub: Alzheimer's and Parkinson's Dis63%
mentions📖Agitation in Alzheimer's Disease60%
mentions📖Alzheimer's Disease60%
mentions📖Alzheimer's Disease Genetic Variants60%
mentions📖Alzheimer's Disease vs Parkinson's Disease Compari60%
mentions📖APP Mutations in Alzheimer's Disease60%
mentions📖DLB, Parkinson's Disease, and Alzheimer's Disease:60%
mentions📖Early-Onset Alzheimer's Disease (EOAD)60%
mentions📖Investment Landscape: Alzheimer's Disease60%
mentions📖Preclinical Alzheimer's Disease60%
mentions📖Prodromal Alzheimer's Disease60%
mentions📖PSEN1 Mutations in Alzheimer's Disease60%
mentions📖PSEN2 Mutations in Alzheimer's Disease60%
mentions📖Sporadic vs Familial Alzheimer's Disease: Comprehensive60%
mentions📖TREM2 Variants in Alzheimer's Disease60%
mentions📖biomarkers60%
related📖Alzheimer's Disease60%
related📖Agitation in Alzheimer's Disease54%
related📖Alzheimer's Disease54%
related📖Alzheimer's Disease Genetic Variants54%
related📖Alzheimer's Disease vs Parkinson's Disease Compari54%
related📖APP Mutations in Alzheimer's Disease54%
related📖DLB, Parkinson's Disease, and Alzheimer's Disease:54%
related📖Early-Onset Alzheimer's Disease (EOAD)54%
related📖Investment Landscape: Alzheimer's Disease54%
related📖Preclinical Alzheimer's Disease54%
related📖Prodromal Alzheimer's Disease54%
related📖PSEN1 Mutations in Alzheimer's Disease54%
related📖PSEN2 Mutations in Alzheimer's Disease54%
related📖Sporadic vs Familial Alzheimer's Disease: Comprehensive54%
related📖TREM2 Variants in Alzheimer's Disease54%
related📖biomarkers54%
related🧫Dairy intake and dementia risk in Malmö Diet and Cancer coho33%
related🧫KEEPS Continuation: Long-term effects of menopausal hormone 33%
related🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer33%
related🧪APOE4 Allosteric Rescue via Small Molecule Chaperones33%
related📖APOE33%