🧫
KEEPS Continuation: Long-term effects of menopausal hormone therapy on AD biomarkers
active
experiment
Created: 2026-04-11T00:48:06
By: experiment_extractor
Quality:
95%
✓ SciDEX
ID: experiment-exp-d003e659-7083-433b-b1e8-b
🧫 Experiment Protocol
Clinical Trialproposed
N = 266
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-11T00:48:06.090741'} |
| p_value | None |
| protocol | Participants from the original KEEPS trial were recontacted 10 years after completion. Amyloid beta burden was assessed using positron emission tomography. Structural MRI was performed to measure hipp |
| effect_size | None |
| sample_size | 266 |
| source_pmid | 41618732 |
| extracted_at | 2026-04-10T17:48:06.087945 |
| _schema_version | 1 |
| experiment_type | clinical_trial |
| success_criteria | Differences in amyloid beta burden and structural MRI biomarkers between hormone therapy groups and placebo |
| expected_outcomes | The study hypothesized that imaging biomarkers would reveal early detection of evolving brain pathology if hormone therapy had long-term effects on AD risk |
| statistical_methods | Statistical comparisons between treatment groups, analysis of APOE ε4 modifying effects |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
47
Outgoing
43
0 supporting
0 contradicting
0 neutral
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