🧫
HFD-induced cognitive dysfunction and neuroinflammation in mice
experiment
Created: 2026-04-10 22:50:30
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-5c1d023e-bee4-43c9-86c7-6
🧫 Experiment Protocol
Animal Model
Related Entities
Metadata
| experiment_type | animal_model |
| protocol | 3-day feeding of 60% HFD vs standard chow, followed by Open Field and Novel Object Recognition behavioral tests, then tissue analysis of CA3 hippocampal region using Western Blotting, PCR, and immunof |
| expected_outcomes | HFD would impair memory performance and reduce α7nAChR expression while increasing neuroinflammation |
| success_criteria | Significant differences in NOR performance and molecular markers between HFD and control groups |
| sample_size | None |
| statistical_methods | None |
| p_value | None |
| effect_size | None |
| extracted_at | 2026-04-10T15:50:30.524109 |
| source_pmid | 41565126 |
| _origin | {'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T22:50:30.528091'} |
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