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E2F regulation of endocycles in hepatocytes

experiment Created: 2026-04-06 12:29:34 By: experiment_extractor Quality: 85% ✓ SciDEX ID: experiment-exp-903cf1dd-d4e8-488e-ba1f-5

🧫 Experiment Protocol Animal Model

Related Entities

E2F1, E2F2, E2F3, E2F7, E2F8

Metadata

experiment_type	animal_model
protocol	lineage-specific cre-mediated gene ablation in hepatocytes, ploidy measurement
expected_outcomes	canonical E2F activator ablation increases ploidy, atypical E2F repressor ablation decreases ploidy
success_criteria	measurable changes in genome ploidy following E2F gene ablation
sample_size	None
statistical_methods	None
p_value	None
effect_size	None
extracted_at	2026-04-06T05:29:34.023410
source_pmid	23064266
_origin	{'type': 'internal', 'url': None, 'tracked_at': '2026-04-06T12:29:34.047540'}