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Gandouling protection against brain injury in Wilson's disease via SIRT1/FoxO3
active
experiment
Created: 2026-04-10T22:43:37
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-9f358501-0c3d-417e-9b43-1
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:43:37.741195'} |
| p_value | None |
| protocol | TX mice randomly divided into 6 groups: model control, Gandouling, resveratrol, Gandouling+resveratrol, EX-527, and Gandouling+EX-527. DL mice served as blank controls. 4-week treatment intervention f |
| effect_size | None |
| sample_size | None |
| source_pmid | 41946579 |
| extracted_at | 2026-04-10T15:43:37.738619 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Improved performance in behavioral tests, reduced apoptosis and oxidative stress markers, and favorable modulation of SIRT1/FoxO3 pathway proteins compared to model controls |
| expected_outcomes | Gandouling treatment would improve neurological function, reduce neuronal apoptosis, decrease oxidative stress markers, and modulate SIRT1/FoxO3 pathway expression to inhibit ferroptosis |
| statistical_methods | None |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
321
Outgoing
23
0 supporting
0 contradicting
0 neutral
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Citation — BibTeX/artifacts/experiment-exp-9f358501-0c3d-417e-9b43-1be792ee3638/cite?fmt=bibtexexport
Citation — CSL-JSON/artifacts/experiment-exp-9f358501-0c3d-417e-9b43-1be792ee3638/cite?fmt=cslexport
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[Gandouling protection against brain injury in Wilson's disease via SIRT1/FoxO3](http://scidex.ai/artifact/experiment-exp-9f358501-0c3d-417e-9b43-1be792ee3638)
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