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SLC7A11 Gene - xCT Cystine/Glutamate Antiporter

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-slc7a11

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Metadata

slug	genes-slc7a11
entity_type	gene
kg_node_id	SLC7A11

Linked Artifacts (94)

mentions🧪Senescence-Induced Lipid Peroxidation Spreading90%

related🧪Senescence-Induced Lipid Peroxidation Spreading90%

mentions🧫Gandouling protection against brain injury in Wilson's 80%

mentions🧪Senescence-Induced Lipid Peroxidation Spreading80%

related🧫Gandouling protection against brain injury in Wilson's 72%

mentions🔬What are the mechanisms underlying senolytic therapy for age70%

mentions🧫Acteoside treatment in LPS-induced SALI mouse model70%

mentions📓ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro70%

related🧫Cytochrome Therapeutics70%

related🧫ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De70%

related🧫Macroautophagy Dysfunction in PD - Experiment Design70%

related🧫Cytochrome Therapeutics70%

related🧫ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De70%

related🧫Macroautophagy Dysfunction in PD - Experiment Design70%

see_also🧪Senescence-Induced Lipid Peroxidation Spreading70%

see_also📓ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro70%

mentions🔬What are the mechanisms underlying senolytic therapy for age63%

related🧫Acteoside treatment in LPS-induced SALI mouse model63%

see_also📖ACSL4 Gene - Acyl-CoA Synthetase Long Chain Family Member 460%

see_also📖HDAC5 Gene60%

see_also📖kdm1a60%

see_also📖NFATc1 — Nuclear Factor of Activated T Cells 160%

see_also📖VKORC1L1 Gene - Vitamin K Epoxide Reductase Complex Subunit 60%

see_also📖Aging vs Neurodegeneration: Mechanistic Comparison Matrix60%

see_also📖TRIM28 (KAP1) Protein60%

see_also📖ACTB Gene60%

see_also📖KIF20A — Kinesin Family Member 20A60%

see_also📖Kynurenine Pathway Modulators for Neurodegeneration60%

see_also📖SLC7A1 Gene60%

see_also📖trim260%

see_also📖DNAJC12 Gene60%

see_also📖UBR5 - Ubiquitin-Protein Ligase E3 Component N-Recognin 560%

see_also📖Kynurenine Pathway Dysregulation in 4R-Tauopathies60%

see_also📖Oxidative Stress Response in 4R-Tauopathies60%

see_also📖NRF2 Activator Therapy60%

related🔬What are the mechanisms underlying senolytic therapy for age56%

related🧪ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro55%

related🧪Circadian-Gated Maresin Biosynthesis Amplification55%

related🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th55%

related🔬What are the mechanisms underlying senolytic therapy for age51%

mentions🧪AMPK hypersensitivity in astrocytes creates enhanced mitocho50%

mentions🧪Circadian-Gated Maresin Biosynthesis Amplification50%

mentions🧪Blood-Brain Barrier SPM Shuttle System50%

mentions🧪Transcriptional Autophagy-Lysosome Coupling50%

mentions🧪ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro50%

mentions🧪Glymphatic System-Enhanced Antibody Clearance Reversal50%

mentions🧪Aquaporin-4 Polarization Rescue50%

mentions🧪Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna50%

mentions🧪Circadian Rhythm Entrainment of Reactive Astrocytes50%

mentions🧪FOXO3-Longevity Pathway Epigenetic Reprogramming50%

mentions🧪HSP90-Tau Disaggregation Complex Enhancement50%

mentions🧪Nutrient-Sensing Epigenetic Circuit Reactivation50%

mentions🧪Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration50%

mentions🧪SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK50%

mentions🧪TFAM overexpression creates mitochondrial donor-recipient gr50%

mentions🧪Magnetosonic-Triggered Transferrin Receptor Clustering50%

mentions🧪CYP46A1 Overexpression Gene Therapy50%

mentions🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th50%

related🔬What are the mechanisms underlying autophagy-lysosome pathwa50%

related🔬What are the mechanisms underlying neuroinflammation resolut50%

related🔬Investigate how lipid raft composition (cholesterol metaboli50%

related🔬What are the mechanisms underlying mitochondrial transfer be50%

related🧫Proposed experiment from debate on Senolytics targeting p16/50%

related🔬What are the mechanisms underlying autophagy-lysosome pathwa50%

related🔬What are the mechanisms underlying neuroinflammation resolut50%

related🔬Investigate how lipid raft composition (cholesterol metaboli50%

related🔬What are the mechanisms underlying mitochondrial transfer be50%

related🔬Analyze circuit-level changes in neurodegeneration using All50%

related🔬Cell type vulnerability in Alzheimers Disease (SEA-AD transc50%

related🧪Extracellular Matrix Stiffness Modulation50%

related🧪Oligodendrocyte White Matter Vulnerability50%

related🔬What are the mechanisms underlying 4r-tau strain-specific sp50%

related🔬What are the mechanisms underlying astrocyte reactivity subt50%

mentions🔬Analyze circuit-level changes in neurodegeneration using All40%

related🧪Senescent Cell Mitochondrial DNA Release40%

related🧪SASP-Mediated Cholinergic Synapse Disruption40%

related🧪SASP-Mediated Complement Cascade Amplification40%

related🧪SASP-Driven Aquaporin-4 Dysregulation40%

related🧪Senescence-Associated Myelin Lipid Remodeling40%

related🧪Senescence-Activated NAD+ Depletion Rescue40%

related🧪CYP46A1 Overexpression Gene Therapy40%

related🧪AMPK hypersensitivity in astrocytes creates enhanced mitocho40%

related🧪Circadian-Gated Maresin Biosynthesis Amplification40%

related🧪Blood-Brain Barrier SPM Shuttle System40%

related🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th40%

related🧪Transcriptional Autophagy-Lysosome Coupling40%

related🧪SASP-Mediated Cholinergic Synapse Disruption40%

related🧪Senescence-Associated Myelin Lipid Remodeling40%

related🔬Senolytics targeting p16/p21+ senescent astrocytes and micro40%

mentions🔬What are the mechanisms underlying autophagy-lysosome pathwa35%

mentions🔬What are the mechanisms underlying neuroinflammation resolut35%

mentions🔬What are the mechanisms underlying mitochondrial transfer be35%

mentions🔬Cell type vulnerability in Alzheimers Disease (SEA-AD transc35%