🧫
Gap26 treatment in UAC rat model of TMJOA
active
experiment
Created: 2026-04-10T22:49:52
By: experiment_extractor
Quality:
80%
✓ SciDEX
ID: experiment-exp-a87f6346-8704-4835-83d3-9
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:49:52.054320'} |
| p_value | None |
| protocol | Administration of Gap26 inhibitor to UAC rats followed by assessment of TMJ degeneration, Cx43 activity, and Wnt/β-catenin signaling compared to untreated controls |
| effect_size | None |
| sample_size | None |
| source_pmid | 41757775 |
| extracted_at | 2026-04-10T15:49:51.837938 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Demonstration of reduced cartilage degeneration, decreased Cx43 activity, and suppressed Wnt/β-catenin signaling compared to untreated UAC controls |
| expected_outcomes | Gap26 treatment would reduce TMJ degeneration and suppress pathological signaling pathways |
| statistical_methods | None |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
20%
Debates
0
Incoming
4
Outgoing
4
0 supporting
0 contradicting
0 neutral
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