🧫
Lifestyle Intervention Mechanisms in Alzheimer's Disease
experiment
Created: 2026-04-02T17:01:41
By: crosslink-v2
Quality:
67%
✓ SciDEX
ID: experiment-exp-wiki-experiments-lifestyl
🧫 Experiment Protocol
Validation
Metadata
| experiment_type | validation |
| source | {'type': 'manual', 'source_name': 'wiki', 'extraction_date': '2026-04-16T01:00:16.899675Z', 'extracted_by': 'backfill_v1'} |
| entities | {'genes': ['BDNF/PPARGC1A/PRKAA1'], 'diseases': ["Alzheimer's Disease"]} |
| model_system | mouse |
| summary | # Lifestyle Intervention Mechanisms in Alzheimer's Disease ## Background and Rationale Alzheimer's disease (AD) affects over 55 million people worldwide, with limited therapeutic options. Epidemiologi |
| replication_status | single_study |
| methodology_notes | Phase 1 (Weeks 1-2): Randomize 200 5xFAD mice (8 weeks old) into 8 groups (n=25 each): control, exercise-only, cognitive-only, diet-only, social-only, and three combination groups. Establish baseline |
| primary_outcome | Validate Lifestyle Intervention Mechanisms in Alzheimer's Disease |
| extraction_metadata | {'extraction_confidence': 0.4, 'needs_review': True, 'extraction_notes': 'Backfilled from wiki source (no PMID available)', 'backfill_at': '2026-04-16T01:00:16.899682'} |
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