📖

calb1

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-calb1

Related Entities

Metadata

slug	genes-calb1
entity_type	gene
kg_node_id	CALB1

Linked Artifacts (320)

see_also📖BEACoN Study - Biomarker Exploration in Aging, Cognition and80%

see_also📖LX1001 Phase 1/2 Trial (NCT03634007) - Gene Therapy for APOE80%

see_also📖LX1001 Long-Term Follow-up (NCT05400330) - Gene Therapy for 75%

see_also📖nct0550878975%

see_also📖remternetug-anti-amyloid-alzheimers75%

see_also📖UPenn Observational Research Repository (NCT04715399)75%

see_also📖APOE4 (Apolipoprotein E4)75%

mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer70%

mentions🧪APOE Isoform Conversion Therapy70%

mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones70%

mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction70%

mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy70%

mentions🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides70%

mentions🧪APOE4-Selective Lipid Nanoemulsion Therapy70%

mentions🧪Competitive APOE4 Domain Stabilization Peptides70%

mentions🧪APOE Isoform Expression Across Glial Subtypes70%

mentions🧪Synthetic Biology BBB Endothelial Cell Reprogramming70%

mentions🧪Mitochondrial Calcium Buffering Enhancement via MCU Modulati70%

see_also📖Cell-Free DNA Biomarkers in Neurodegeneration70%

see_also📖Exosomal Biomarkers in Neurodegeneration70%

see_also📖Exosomal miR-155 in Neurodegeneration70%

see_also📖IL-6 (Interleukin-6) in Neurodegeneration70%

see_also📖Liquid Biopsy in Neurodegeneration70%

see_also📖Metabolomic Biomarkers in Neurodegeneration70%

see_also📖Neuroimaging Biomarkers for Neurodegeneration70%

see_also📖Synaptic Biomarkers in Neurodegeneration70%

see_also📖ALA-enriched Nutrition for APOE4 Carriers with MCI (NCT0739270%

see_also📖Olfactory Mucosa, Blood and Urine for Identification of Earl70%

see_also📖Swedish BioFINDER 2 Study: Biomarkers and Neurodegeneration 70%

see_also📖APOE2 (Apolipoprotein E2)70%

see_also📖APOE3 (Apolipoprotein E3)70%

see_also📖Beta-Propeller Protein-Associated Neurodegeneration (BPAN)70%

see_also📖China Neurodegeneration Epidemiology70%

see_also📖DALY Methodology — Neurodegeneration70%

see_also📖Disease Progression & Staging in Neurodegeneration70%

see_also📖Economic Burden — Neurodegeneration70%

see_also📖European Neurodegeneration Epidemiology70%

see_also📖Familial vs Sporadic Neurodegeneration Comparison70%

see_also📖Global Neurodegeneration Epidemiology70%

see_also📖India Neurodegeneration Epidemiology70%

see_also📖Japan Neurodegeneration Epidemiology70%

see_also📖Manganese-Related Neurodegeneration (Manganism)70%

see_also📖mitochondrial-dysfunction-neurodegeneration-comparison70%

see_also📖Mitochondrial Diseases and Neurodegeneration Comparison Matr70%

see_also📖Mitochondrial Membrane Protein-Associated Neurodegeneration 70%

see_also📖Neurodegeneration with Brain Iron Accumulation (NBIA)70%

see_also📖Potential Impact Measures — Neurodegeneration70%

see_also📖Pantothenate Kinase-Associated Neurodegeneration (PKAN)70%

see_also📖PLA2G6-Associated Neurodegeneration (PLAN)70%

see_also📖Sleep Disorders in Neurodegeneration70%

see_also📖US Neurodegeneration Epidemiology70%

see_also📖Extracellular Vesicle and Tunneling Nanotube-Mediated Spread70%

see_also📖acetylcholine-signaling-neurodegeneration70%

see_also📖Advanced Glycation End Products in Neurodegeneration70%

see_also📖Advanced In Vitro Models for Neurodegeneration — Organoids, 70%

see_also📖Amylin Signaling in Neurodegeneration70%

see_also📖Antibody Therapy in Neurodegeneration70%

see_also📖Antisense Oligonucleotide (ASO) Therapy in Neurodegeneration70%

see_also📖Autosis Pathway in Neurodegeneration70%

see_also📖Axon Guidance Pathways in Neurodegeneration70%

see_also📖Basal Ganglia Circuit Dysfunction in Neurodegeneration70%

see_also📖becn1-autophagy-initiation-neurodegeneration-causal-chain70%

see_also📖CaMKII Signaling Pathway in Neurodegeneration70%

see_also📖Carbonic Anhydrase Modulator Therapy in Neurodegeneration70%

see_also📖Cerebral Amyloid Angiopathy in Neurodegeneration70%

see_also📖Cerebral Amyloid Angiopathy Pathway in Neurodegeneration70%

see_also📖Cholinergic System Dysfunction in Neurodegeneration70%

see_also📖Chrononutrition and Time-Restricted Eating in Neurodegenerat70%

see_also📖Neural Circuits in Neurodegeneration70%

see_also📖Cognitive Reserve and Resilience in Neurodegeneration70%

see_also📖Computational Disease Models for Neurodegeneration70%

see_also📖Convergent Pathways in Neurodegeneration70%

see_also📖Copper Homeostasis in Neurodegeneration70%

see_also📖COVID-19 Neurodegeneration Mechanism70%

see_also📖Diffusion MRI (DTI) in Neurodegeneration70%

see_also📖Digital Phenotyping in Neurodegeneration70%

see_also📖Down Syndrome Neurodegeneration Pathway70%

see_also📖Dystrophic Neurites in Neurodegeneration70%

see_also📖Endocannabinoid System in Neurodegeneration70%

see_also📖Endosomal-Lysosomal Pathway in Neurodegeneration70%

see_also📖Endosomal Sorting Defects in Neurodegeneration70%

see_also📖Endothelin Signaling Pathway in Neurodegeneration70%

see_also📖epigenetics-neurodegeneration70%

see_also📖ESCRT-III Inhibition by Alpha-Synuclein in Neurodegeneration70%

see_also📖FA2H-Associated Neurodegeneration Pathway70%

see_also📖Farnesoid X Receptor (FXR) Signaling in Neurodegeneration70%

see_also📖Galectin-3 Mechanism in Neurodegeneration70%

see_also📖Gangliosides in Neurodegeneration70%

see_also📖GDF15/GDF11 Signaling in Neurodegeneration70%

see_also📖GDNF Signaling Pathway in Neurodegeneration70%

see_also📖Ghrelin Signaling Pathway in Neurodegeneration70%

see_also📖Glucocorticoid Signaling Pathway in Neurodegeneration70%

see_also📖Glycosylation in Neurodegeneration70%

see_also📖gp130/IL-6 Family Cytokine Signaling in Neurodegeneration70%

see_also📖Hippocampal Neurogenesis in Neurodegeneration70%

see_also📖Histone Modification Pathways in Neurodegeneration70%

see_also📖HMGB1 Signaling in Neurodegeneration70%

see_also📖Homocysteine Neurotoxicity and Neurodegeneration70%

see_also📖IGF-1 Signaling Pathway in Neurodegeneration70%

see_also📖IL-1 Signaling Pathway in Neurodegeneration70%

see_also📖Integrated Stress Response in Neurodegeneration70%

see_also📖interleukin-6-signaling-neurodegeneration70%

see_also📖Intrinsic Apoptosis Pathway in Neurodegeneration70%

see_also📖Ion Channel Dysfunction in Neurodegeneration: Cross-Disease 70%

see_also📖Kidney-Brain Neurodegeneration Axis70%

see_also📖Lipid Dysregulation in Neurodegeneration70%

see_also📖Lipid Metabolism Dysregulation in Neurodegeneration70%

see_also📖Lysosomal Calcium Dysregulation in Neurodegeneration70%

see_also📖Magnetic Resonance Spectroscopy in Neurodegeneration70%

see_also📖Metal Homeostasis Dysregulation in Neurodegeneration70%

see_also📖Metal Homeostasis in Neurodegeneration70%

see_also📖Microglial Priming Pathway in Neurodegeneration70%

see_also📖MicroRNA Dysfunction in Neurodegeneration70%

see_also📖Mineralocorticoid Receptor Signaling in Neurodegeneration70%

see_also📖Mitochondrial Dynamics Pathway in Neurodegeneration70%

see_also📖Mitochondrial Fusion in Neurodegeneration70%

see_also📖Molecular Chaperones in Neurodegeneration70%

see_also📖mTOR Signaling in Neurodegeneration70%

see_also📖mTOR Signaling Pathway in Neurodegeneration70%

see_also📖Neural Circuit Disruption in Neurodegeneration70%

see_also📖Neurexin/Neuroligin Synaptic Adhesion Modulator Therapy in N70%

see_also📖Neurofilament Light Chain (NfL) Mechanism in Neurodegenerati70%

see_also📖Neuronal Hyperexcitability in Neurodegeneration70%

see_also📖Neuropil Threads in Neurodegeneration70%

see_also📖Neurotensin Signaling in Neurodegeneration70%

see_also📖Neurovascular Unit Dysfunction in Neurodegeneration70%

see_also📖NF-kB Signaling Pathway in Neurodegeneration70%

see_also📖Nitric Oxide Signaling in Neurodegeneration70%

see_also📖Noradrenergic Signaling Pathway in Neurodegeneration70%

see_also📖Neuropeptide Y Signaling in Neurodegeneration70%

see_also📖NRF2 Signaling Pathway in Neurodegeneration70%

see_also📖Nuclear Pore Complex Dysfunction in Neurodegeneration70%

see_also📖Orexin Signaling in Neurodegeneration70%

see_also📖OSK Reprogramming and Yamanaka Factors in Neurodegeneration70%

see_also📖P-Body (Processing Body) Pathway in Neurodegeneration70%

see_also📖Paranodal Dysfunction in Neurodegeneration70%

see_also📖Paraptosis in Neurodegeneration70%

see_also📖Parthanatos in Neurodegeneration70%

see_also📖Pericyte Loss in Neurodegeneration70%

see_also📖Peripheral Immune-Brain Crosstalk in Neurodegeneration70%

see_also📖PKR Pathway in Neurodegeneration70%

see_also📖PPAR Signaling Pathway in Neurodegeneration70%

see_also📖Prion Diseases in Neurodegeneration70%

see_also📖Prion-Like Spread in Neurodegeneration70%

see_also📖Prion Protein Metabolism in Neurodegeneration70%

see_also📖Progesterone Signaling Pathway in Neurodegeneration70%

see_also📖Prognostic Biomarkers in Neurodegeneration70%

see_also📖Protein Aggregation Comparison in Neurodegeneration70%

see_also📖Protein Aggregation Seeds in Neurodegeneration70%

see_also📖Protein O-GlcNAcylation Pathway in Neurodegeneration70%

see_also📖Cortical Involvement and Neurodegeneration in Progressive Su70%

see_also📖Purinergic Signaling in Neurodegeneration70%

see_also📖Quantum Biology and Coherent Energy Transfer in Neurodegener70%

see_also📖R-Loop Stress in Neurodegeneration70%

see_also📖RAN Translation in Neurodegeneration70%

see_also📖Retinal Degeneration Pathway in Neurodegeneration70%

see_also📖Ribosome Dysfunction in Neurodegeneration70%

see_also📖RNA Splicing in Neurodegeneration70%

see_also📖RNA-Targeted Therapies in Neurodegeneration70%

see_also📖Ribonuclease κ and Circular RNAs: A New Mechanism of Aging a70%

see_also📖S100 Protein Signaling Pathway in Neurodegeneration70%

see_also📖Senescent Cell Clearance in Neurodegeneration70%

see_also📖Serotonergic Dysfunction in Neurodegeneration70%

see_also📖Sex Differences in Neurodegeneration70%

see_also📖Short Chain Fatty Acids in Neurodegeneration70%

see_also📖Sigma-1 Receptor Signaling in Neurodegeneration70%

see_also📖Sirtuin-Mitochondrial Biogenesis Axis in Neurodegeneration70%

see_also📖Sleep Dysfunction in Neurodegeneration70%

see_also📖SUMOylation in Neurodegeneration70%

see_also📖synaptic-vesicle-cycling-neurodegeneration70%

see_also📖Synthetic Lethality and PARP Inhibition in Neurodegeneration70%

see_also📖T-Cell Dysfunction in Neurodegeneration70%

see_also📖Tertiary Lymphoid Organs in Neurodegeneration70%

see_also📖Therapeutic Targets in Neurodegeneration70%

see_also📖Transdiagnostic Proteomic Changes in Neurodegeneration70%

see_also📖ubiquitin-proteasome-dysfunction-neurodegeneration70%

see_also📖Ubiquitin-Proteasome System Dysfunction in Neurodegeneration70%

see_also📖Vagus Nerve Pathway in Neurodegeneration70%

see_also📖VEGF Signaling and Cerebral Angiogenesis in Neurodegeneratio70%

see_also📖vip-vasoactive-intestinal-peptide-signaling-neurodegeneratio70%

see_also📖WNK1-Bilirubin Signaling in Neuroinflammation and Neurodegen70%

see_also📖WNK1 Kinase in Neurodegeneration70%

see_also📖Wnt/β-Catenin Signaling Pathway in Neurodegeneration70%

mentions🧪Sleep Spindle-Synaptic Plasticity Enhancement65%

mentions🧪Excitatory Neuron Vulnerability via SLC17A7 Downregulation65%

mentions🧪Mitochondrial RNA Granule Rescue Pathway65%

related🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides63%

related🧪Synthetic Biology BBB Endothelial Cell Reprogramming63%

related🧪Mitochondrial Calcium Buffering Enhancement via MCU Modulati63%

related🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer60%

related🧪APOE Isoform Conversion Therapy60%

related🧪APOE4 Allosteric Rescue via Small Molecule Chaperones60%

related🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction60%

related🧪Targeted APOE4-to-APOE3 Base Editing Therapy60%

related🧪APOE4-Selective Lipid Nanoemulsion Therapy60%

related🧪Competitive APOE4 Domain Stabilization Peptides60%

related🧪APOE Isoform Expression Across Glial Subtypes60%

related🧪Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna60%

related🧪Sleep Spindle-Synaptic Plasticity Enhancement60%

related🧪GFAP-Positive Reactive Astrocyte Subtype Delineation60%

related🧪Lysosomal Enzyme Trafficking Correction60%

related🧪Prefrontal sensory gating circuit restoration via PV interne60%

related🧪Excitatory Neuron Vulnerability via SLC17A7 Downregulation60%

related🧪Mitochondrial RNA Granule Rescue Pathway60%

see_also📖Astrocytes60%

see_also📖CREB1 Gene60%

see_also📖NTF3 — Neurotrophin-360%

see_also📖NTRK3 Gene60%

see_also📖CACNA1C Gene60%

see_also📖CACNA1G Gene60%

see_also📖CAV160%

see_also📖cct460%

see_also📖GRIN2B — NMDA Receptor Subunit 2B60%

see_also📖ids60%

see_also📖KCNN3 — Potassium Calcium-Activated Channel Subfamily N Memb60%

see_also📖PRDX3 — Peroxiredoxin 360%

see_also📖RNF14 — Ring Finger Protein 1460%

see_also📖SFPQ Gene60%

see_also📖slc17a7 Gene60%

see_also📖SMARCB1 — SWI/SNF Related Matrix Associated Actin Dependent 60%

see_also📖SSBP1 Gene60%

see_also📖stxbp360%

see_also📖SYNE2 Gene60%

see_also📖TMEM59 Gene60%

see_also📖ULK2 Gene60%

see_also📖hypotheses-apoe-contributes-alzheimers-disease-regulat60%

see_also📖APP Gene Dosage Reduction Therapy for Down Syndrome60%

see_also📖Alzheimer Indonesia60%

see_also📖Packard Center for ALS Research60%

see_also📖BDNF Gene60%

see_also📖CALB2 Gene60%

see_also📖Glutamate Decarboxylase 160%

see_also📖Adipose-Derived Mesenchymal Stem Cell Therapy for Early Alzh55%

see_also📖NCT07477431 - Levetiracetam for Persons at Risk for Alzheime55%

see_also📖TRAILRUNNER-ALZ 1: Remternetug for Early Alzheimer's Di55%

related🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer54%

related🧪APOE Isoform Conversion Therapy54%

related🧪APOE4 Allosteric Rescue via Small Molecule Chaperones54%

related🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction54%

related🧪Targeted APOE4-to-APOE3 Base Editing Therapy54%

related🧪APOE4-Selective Lipid Nanoemulsion Therapy54%

related🧪Competitive APOE4 Domain Stabilization Peptides54%

related🧪APOE Isoform Expression Across Glial Subtypes54%

related🧪Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna54%

related🧪Sleep Spindle-Synaptic Plasticity Enhancement54%

related🧪GFAP-Positive Reactive Astrocyte Subtype Delineation54%

related🧪Prefrontal sensory gating circuit restoration via PV interne54%

related🧪Excitatory Neuron Vulnerability via SLC17A7 Downregulation54%

related🔬What are the mechanisms underlying apoe4 structural biology 50%

related🔬What are the mechanisms underlying autophagy-lysosome pathwa50%

related🔬What are the mechanisms underlying mechanistic role of apoe 50%

related🔬What are the mechanisms underlying sleep disruption as cause50%

related🔬What are the mechanisms underlying rna binding protein dysre50%

related🔬Analyze circuit-level changes in neurodegeneration using All50%

related🔬SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas50%

related🔬What are the mechanisms underlying apoe4 structural biology 50%

related🔬What are the mechanisms underlying rna binding protein dysre50%

related🔬Analyze circuit-level changes in neurodegeneration using All50%

related🔬What are the mechanisms underlying sleep disruption as cause50%

related🔬What are the mechanisms underlying autophagy-lysosome pathwa50%

related🔬What are the mechanisms underlying mechanistic role of apoe 50%

related🔬SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas50%

see_also📖al002-trem2-agonist-alzheimers50%

see_also📖CORT108297 Phase 2 (NCT04601038) - Stress Attenuation in AD50%

see_also📖DBS Nucleus Basalis Trial (NCT07218081): Deep Brain Stimulat50%

see_also📖Donanemab TRAILBLAZER-ALZ 2 Trial50%

see_also📖MK-1167 Phase 2 AD Trial (MK-1167-008)50%

see_also📖A Placebo-Controlled, Double-Blind, Parallel-Group, 18-Month50%

see_also📖A Phase IIB, Randomized, Double-Blind, Placebo-Controlled, M50%

see_also📖A Phase 2 Double-Blind, Randomized, Placebo-Controlled Trial50%

see_also📖Trontinemab (RO7126209) Phase 3 Trial — TRONTIER 2 (NCT0717050%

see_also📖UB-311 Alzheimer's Vaccination Trial50%

related🧫s:** - Biochemical binding assays measuring PROTAC selectivi45%

related🧫Why Does Amyloid Removal Only Slow Decline 27%? — Mechanisti45%

related🧫Down Syndrome Alzheimer's Disease: Mechanisms and Thera45%

related🧫s:** - Temporal analysis showing mitochondrial defects prece45%

related🧫Proposed experiment from debate on TDP-43 undergoes liquid-l45%

related🧫Axonal Transport Dysfunction Validation in Parkinson's 45%

related🧫Stress Granule Dysfunction Validation in Parkinson's Di45%

related🧫ApoE4 Function in Alzheimer's Disease45%

related🧫Metal Ion Homeostasis Dysregulation in Alzheimer's Dise45%

related🧫Migraine Cortical Hyperexcitability and Alzheimer's Dis45%

related🧫s:** - Test whether HCN1 knockout specifically in EC layer I45%

related🧫Brain Connectivity-Targeted tACS Trial in Early AD45%

related🧫AD Amyloid-Resilient Phenotype Study — Why Some amyloid-Posi45%

related🧫AD Combination Therapy Trial: Anti-Aβ + Anti-Tau45%

related🧫Animal Model Comparison for Neurodegenerative Disease Therap45%

related🧫Biomarker-Guided Sequential Therapy Selection in Alzheimer&#45%

related🧫tACS Connectivity Trial in Early Alzheimer's45%

related🧫Brain Connectivity-Targeted tACS Trial in Early AD45%

related🧫Cognitive Reserve Mechanisms in Alzheimer's Disease — M45%

related🧫Cholinergic System Dysfunction in DLB — Mechanisms and Thera45%

related🧫Lifestyle Intervention Mechanisms in Alzheimer's Diseas45%

related🧫Neural Stem Cell Therapy for Alzheimer's Disease45%

related🧫Sex Differences in Alzheimer's Disease — mechanisms and45%

related🧫DLB Cognitive Fluctuation Mechanism Experiment45%

related🧫Neural Oscillation Dysfunction Validation in Parkinson'45%

related🧫Non-Motor Symptom Progression in Parkinson's Disease — 45%

related🧫Sleep and Circadian Dysfunction as Driver of Neurodegenerati45%

related🧫Sleep Disruption and Alzheimer's Disease — mechanism an45%

related🧫Sleep and Respiratory Network Interaction in ALS — Experimen45%

related🧫Biomechanical Impact Profiles and Chronic Traumatic Encephal45%

related🧫Blood-Based Biomarker Panel for Early AD Detection45%

related🧫CRISPR Gene Correction Approaches for CBS/PSP45%

related🧫Chaperone-Mediated Autophagy Dysfunction in PD - Experiment 45%

related🧫Presymptomatic GRN Carrier Intervention Timing — Biomarker-G45%

related🧫Proteasome-Ubiquitin System Dysfunction Validation in Parkin45%

related🧫TMEM106B Haplotype as Genetic Modifier in FTD — Mechanism an45%

see_also📖Cannabidiol for Alzheimer's Disease Prevention (NCT058245%

see_also📖EI-1071 Immunomodulator for Alzheimer's Disease (NCT06745%

see_also📖KarXT for Alzheimer's Disease Cognitive Impairment - MI45%

see_also📖A Phase 3, Randomised, Double-blinded, Placebo-controlled St45%

see_also📖Novartis Alzheimer's Disease Phase 2 Trial (NCT0709451645%

see_also📖Rotigotine and Rivastigmine Combination Therapy for Alzheime45%

mentions🔬Analyze circuit-level changes in neurodegeneration using All40%

related🧪Lysosomal Enzyme Trafficking Correction40%

related🧪Mitochondrial RNA Granule Rescue Pathway40%