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Guhan Yangsheng Jing alleviates sleep deprivation-induced neuronal injury via neurotransmitter rebalancing, mitochondrial protection, and inhibition of pyroptosis.
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ID: paper-41539636
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Guhan Yangsheng Jing alleviates sleep deprivation-induced neuronal injury via neurotransmitter rebalancing, mitochondrial protection, and inhibition of pyroptosis.
["Fu X", "Long Q", "Wang Z", "Yan S", "Li L", "Liu L", "Hu Z", "Zeng X", "Zhu X", "Jiang J"]
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: Sleep deprivation is a growing public health burden linked to neuroinflammation, oxidative stress, and neurodegeneration. While conventional hypnotics provide transient relief, their long-term use is limited by tolerance and adverse effects. Guhan Yangsheng Jing (GHYSJ), a classical multi-herbal prescription from traditional Chinese medicine, has been clinically used to relieve insomnia and fatigue, yet its neuroprotective mechanisms remain unclear. OBJECTIVE: Thi...
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