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Ganglion Cell Layer Compared With Inner Plexiform Layer Atrophy After Optic Neuritis Associated With NMOSD, MOGAD, and MS.
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ID: paper-41881459
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Ganglion Cell Layer Compared With Inner Plexiform Layer Atrophy After Optic Neuritis Associated With NMOSD, MOGAD, and MS.
Filippatou AG, Gakis G, Bacchetti A, Kim A, Said Y, McCormack B, Lin TY, Didouchevski A, Pellegrini N, Fitzgerald KC, Calabresi PA, Saidha S, Sotirchos ES
Abstract
BACKGROUND AND OBJECTIVES: Optic neuritis (ON) is a common manifestation of multiple sclerosis (MS), aquaporin-4-IgG seropositive neuromyelitis optica spectrum disorder (AQP4+NMOSD), and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). Compared with MS-ON, AQP4-ON and MOGAD-ON eyes exhibit more severe thinning of the macular composite ganglion cell + inner plexiform layer (GCIPL), as measured by optical coherence tomography (OCT). The individual measurement of the ganglio...
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