Circadian abnormalities, molecular clock gene and chronobiological treatment for psychiatric disorders.

Anomalies of the circadian rhythm are important in mental illnesses such as anxiety, schizophrenia, bipolar disorder, and depression. Dysregulated molecular clock genes, including CLOCK, BMAL1, PER, and CRY, are frequently linked to disturbances in hormone production, sleep-wake cycles, and neurotransmitter modulation. These genes affect mood, thought, and behaviour by controlling the body's internal clock. Circadian system dysfunctions can worsen mental health issues by impairing cognitive func...