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TFEB

wiki page Created: 2026-04-02T07:32:08 By: import Quality: 70% ✓ SciDEX ID: wiki-TFEB

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Metadata

entity_type	protein
neurowiki_url	https://neurowiki.xyz/search?q=TFEB
summary	A protein referenced in 2 knowledge graph relationships. Key connections: promotes lysosomal_biogenesis (mechanism); semaglutide (drug) activates.

Linked Artifacts (42)

mentions🧪The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction90%

mentions🧪TFEB-PGC1α Mitochondrial-Lysosomal Decoupling90%

related🧪The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction81%

related🧪TFEB-PGC1α Mitochondrial-Lysosomal Decoupling81%

see_also🧪The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction80%

see_also🧪TFEB-PGC1α Mitochondrial-Lysosomal Decoupling80%

mentions🔬What are the mechanisms underlying microglia-astrocyte cross65%

mentions🔬What are the mechanisms underlying autophagy-lysosome pathwa65%

mentions🔬What are the mechanisms underlying what are the mechanisms b65%

mentions🔬What are the mechanisms underlying mechanistic role of apoe 65%

mentions🔬What are the mechanisms underlying sleep disruption as cause65%

mentions🔬What are the mechanisms underlying mitochondrial transfer be65%

mentions🔬What gene expression changes in the aging mouse brain predic65%

mentions🔬Investigate prion-like spreading of tau pathology through co65%

mentions🔬How does metabolic reprogramming (glucose metabolism shifts,65%

related🧪The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction60%

related🧪TFEB-PGC1α Mitochondrial-Lysosomal Decoupling60%

mentions🧪RAB27A-dependent extracellular vesicle engineering for mitoc50%

mentions🧪AMPK hypersensitivity in astrocytes creates enhanced mitocho50%

mentions🧪APOE-Dependent Autophagy Restoration50%

mentions🧪Heat Shock Protein 70 Disaggregase Amplification50%

mentions🧪Autophagosome Maturation Checkpoint Control50%

mentions🧪Lysosomal Membrane Repair Enhancement50%

mentions🧪Lysosomal Calcium Channel Modulation Therapy50%

mentions🧪Transcriptional Autophagy-Lysosome Coupling50%

mentions🧪TREM2-mediated microglial tau clearance enhancement50%

mentions🧪Lysosomal Enzyme Trafficking Correction50%

mentions🧪Ephrin-B2/EphB4 Axis Manipulation50%

mentions🧪Microbiome-Derived Tryptophan Metabolite Neuroprotection50%

mentions🧪SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK50%

related🔬What are the mechanisms underlying microglia-astrocyte cross50%

related🔬What are the mechanisms underlying autophagy-lysosome pathwa50%

related🔬What are the mechanisms underlying what are the mechanisms b50%

related🔬What are the mechanisms underlying mechanistic role of apoe 50%

related🔬What are the mechanisms underlying sleep disruption as cause50%

related🔬What are the mechanisms underlying mitochondrial transfer be50%

related🔬What gene expression changes in the aging mouse brain predic50%

related🔬Investigate prion-like spreading of tau pathology through co50%

related🔬How does metabolic reprogramming (glucose metabolism shifts,50%

related🔬What are the mechanisms underlying 4r-tau strain-specific sp40%

related🔬What are the mechanisms underlying tdp-43 phase separation t40%

related🔬Cell type vulnerability in Alzheimers Disease (SEA-AD transc40%