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Apolipoprotein C-I

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-proteins-apoc1-protein

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slug	proteins-apoc1-protein
entity_type	protein
kg_node_id	APOC1PROTEIN

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Linked Artifacts (61)

mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer70%

mentions🧪APOE Isoform Conversion Therapy70%

mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones70%

related🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer63%

related🧪APOE Isoform Conversion Therapy63%

related🧪APOE4 Allosteric Rescue via Small Molecule Chaperones63%

see_also📖Neurodegeneration60%

mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%

mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%

mentions🧪APOE4-Selective Lipid Nanoemulsion Therapy50%

mentions🧪Competitive APOE4 Domain Stabilization Peptides50%

mentions🧪APOE Isoform Expression Across Glial Subtypes50%

mentions🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides50%

mentions🧪Heat Shock Protein 70 Disaggregase Amplification50%

mentions🧪Serine/Arginine-Rich Protein Kinase Modulation50%

mentions🧪Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m50%

related🔬What are the mechanisms underlying blood-brain barrier trans50%

related🔬What are the mechanisms underlying mitochondrial transfer be50%

related🔬What are the mechanisms underlying tdp-43 phase separation t50%

related🔬What are the mechanisms underlying blood-brain barrier trans50%

related🔬What are the mechanisms underlying protein aggregation cross50%

related🔬What are the mechanisms underlying rna binding protein dysre50%

related🔬What are the mechanisms underlying mitochondrial transfer be50%

related🔬Analyze circuit-level changes in neurodegeneration using All50%

related🔬RNA binding protein dysregulation across ALS FTD and AD50%

related🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%

related🧪APOE Isoform Conversion Therapy50%

related🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%

see_also📖Adipose-Derived Mesenchymal Stem Cell Therapy for Early Alzh45%

see_also📖al002-trem2-agonist-alzheimers45%

see_also📖BEACoN Study - Biomarker Exploration in Aging, Cognition and45%

see_also📖CORT108297 Phase 2 (NCT04601038) - Stress Attenuation in AD45%

see_also📖DBS Nucleus Basalis Trial (NCT07218081): Deep Brain Stimulat45%

see_also📖Donanemab TRAILBLAZER-ALZ 2 Trial45%

see_also📖NCT07477431 - Levetiracetam for Persons at Risk for Alzheime45%

see_also📖MK-1167 Phase 2 AD Trial (MK-1167-008)45%

see_also📖LX1001 Phase 1/2 Trial (NCT03634007) - Gene Therapy for APOE45%

see_also📖A Placebo-Controlled, Double-Blind, Parallel-Group, 18-Month45%

see_also📖A Phase IIB, Randomized, Double-Blind, Placebo-Controlled, M45%

see_also📖LX1001 Long-Term Follow-up (NCT05400330) - Gene Therapy for 45%

see_also📖TRAILRUNNER-ALZ 1: Remternetug for Early Alzheimer's Di45%

see_also📖nct0550878945%

see_also📖A Phase 2 Double-Blind, Randomized, Placebo-Controlled Trial45%

see_also📖ALA-enriched Nutrition for APOE4 Carriers with MCI (NCT0739245%

see_also📖remternetug-anti-amyloid-alzheimers45%

see_also📖Trontinemab (RO7126209) Phase 3 Trial — TRONTIER 2 (NCT0717045%

see_also📖UB-311 Alzheimer's Vaccination Trial45%

see_also📖UPenn Observational Research Repository (NCT04715399)45%

see_also📖APOE2 (Apolipoprotein E2)45%

see_also📖APOE3 (Apolipoprotein E3)45%

see_also📖APOE4 (Apolipoprotein E4)45%

mentions📖Arrowhead Pharmaceuticals40%

mentions🔬What are the mechanisms underlying protein aggregation cross40%

mentions🔬What are the mechanisms underlying rna binding protein dysre40%

mentions🔬RNA binding protein dysregulation across ALS FTD and AD40%

mentions🔬Analyze circuit-level changes in neurodegeneration using All40%

related🧪Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m40%

related🧪Heat Shock Protein 70 Disaggregase Amplification40%

related🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides40%

related🧪Serine/Arginine-Rich Protein Kinase Modulation40%

related🔬What are the mechanisms underlying tdp-43 phase separation t30%