protein 668 words KG: APOC1PROTEIN
Contents

Apolipoprotein C-I

🔬 Protein Info
Gene SymbolAPOC1PROTEIN
Full NameApolipoprotein C-I
Chromosome19.
Protein FamilyApolipoprotein family
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionvarious brain regions and cell types
Molecular Weight9 kDa
UniProt IDP02654
GeneCardsAPOC1PROTEIN
Human Protein AtlasAPOC1PROTEIN
Associated Diseasesneurodegeneration
InteractionsABCA1, ABCA2, APOA1, APOC2, APOC3, APOD
KG Connections113 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

UniProtWikipedia

Related Hypotheses (12)

Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
APOE Isoform Conversion Therapy
Score: 0.72
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (7)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
al002-trem2-agonist-alzheimers
clinical_trial · Pages share 3 hypotheses
BEACoN Study - Biomarker Exploration in Aging, Cognitio
clinical · Pages share 3 hypotheses
CORT108297 Phase 2 (NCT04601038) - Stress Attenuation i
clinical · Pages share 3 hypotheses
DBS Nucleus Basalis Trial (NCT07218081): Deep Brain Sti
clinical · Pages share 3 hypotheses

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.