🧫

Machine learning-based identification of C1Q hub genes

active
experiment Created: 2026-04-06T12:27:51 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-9bf7bb8f-2c69-4a0c-880d-2
🧫 Experiment Protocol Gene Expressionproposed
Related Entities
C1QA, C1QC
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-06T12:27:51.977370'}
p_valueNone
protocolApplication of GBM, LASSO, and XGBoost algorithms on bulk RNA data, followed by generalized linear modeling and ROC analysis
effect_sizeNone
sample_sizeNone
source_pmid38179058
extracted_at2026-04-06T05:27:51.955977
_schema_version1
experiment_typegene_expression
success_criteriaSatisfactory diagnostic accuracy in both training and validation cohorts
expected_outcomesSelection of most predictive C1Q-related genes for atherosclerosis diagnosis
statistical_methodsGBM, LASSO regression, XGBoost, generalized linear models, ROC analysis
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
37
Outgoing
41
0 supporting 0 contradicting 0 neutral
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