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AD/PD 2026 Poster and Abstract Highlights
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Dates: March 17-21, 2026 Location: Copenhagen, Denmark Organizer: Kenes Group
Overview
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The poster and abstract sessions at AD/PD 2026 featured hundreds of presentations from researchers worldwide, showcasing the latest findings in basic science, clinical research, and therapeutic development for Alzheimer's and Parkinson's diseases["@adpd2026"][@chen2023].
Alzheimer's Disease Abstracts
Amyloid and APP Biology
Novel Mechanisms
...
Dates: March 17-21, 2026 Location: Copenhagen, Denmark Organizer: Kenes Group
Overview
Mermaid diagram (expand to render)
The poster and abstract sessions at AD/PD 2026 featured hundreds of presentations from researchers worldwide, showcasing the latest findings in basic science, clinical research, and therapeutic development for Alzheimer's and Parkinson's diseases["@adpd2026"][@chen2023].
Alzheimer's Disease Abstracts
Amyloid and APP Biology
Novel Mechanisms
- APP processing variants: Rare genetic variants affecting amyloid generation
- Alpha-secretase regulation: New insights into ADAM10/ADAM17 activity
- Amyloid oligomer toxicity: Cell-based models of amyloid species
- APOE4 effects: Mechanisms of APOE4-mediated risk
Therapeutic Approaches
- Antibody engineering: Next-generation anti-amyloid antibodies
- BACE inhibitor alternatives: Novel gamma-secretase modulators
- Small molecule aggregators: Anti-aggregation compound screening
- Combination strategies: Multi-target approach development
Tau Pathology and Therapeutics
Basic Science
- Tau post-translational modifications: Acetylation, methylation, and truncation
- Tau propagation mechanisms: Cell-to-cell transmission pathways
- Tau isoforms: Differential toxicity of 3R and 4R tau
- Tau PET correlations: Imaging-pathology correlations
Clinical
- Tau PET longitudinal studies: Disease progression markers
- Anti-tau antibody results: Safety and efficacy data
- Tau aggregation inhibitors: Phase 1/2 results
- Biomarker correlations: Fluid and imaging biomarkers
Neuroinflammation
Microglial Biology
- [TREM2](/proteins/trem2) biology: Agonist and antagonist approaches
- DAM pathway: Disease-associated microglia phenotypes
- Microglial priming: Age-related activation changes
- CX3CR1 modulation: Fractalkine receptor targeting
Complement System
- C1q inhibition: Synaptic protection approaches
- C3 therapeutics: Complement-mediated inflammation
- Microglia-neuron crosstalk: Synaptic maintenance mechanisms
Biomarkers and Diagnostics
Fluid Biomarkers
- p-tau217: Clinical utility and standardization
- p-tau181: Cross-platform validation
- NfL: Neurodegeneration monitoring
- Neurogranin: Synaptic damage markers
Novel Approaches
- Extracellular vesicles: Biomarker cargo
- Multiplex platforms: Multi-analyte panels
- Point-of-care tests: Rapid diagnostics
Parkinson's Disease Abstracts
Alpha-Synuclein Research
Basic Mechanisms
- Aggregation kinetics: Seed amplification studies
- Oligomer species: Toxic intermediate characterization
- Propagation pathways: Prion-like spread mechanisms
- Lewy body composition: Structural analysis
Therapeutics
- Immunotherapy approaches: Active and passive immunization
- Small molecule inhibitors: Aggregation blockers
- Gene therapy: SNCA targeting strategies
- Cell therapy: Dopaminergic cell replacement
Genetic Subtypes
LRRK2
- LRRK2 biology: Kinase function and regulation
- Inhibitor development: Clinical candidate updates
- Biomarker development: pS935-LRRK2 as PD marker
- Genetic stratification: Patient selection for trials
GBA
- GBA mutations: Frequency and phenotypic effects
- Gaucher-PD connection: Mechanism of risk
- Substrate reduction: Therapeutic approaches
- Enzyme enhancement: Pharmacological chaperones
Mitochondrial Dysfunction
Mitophagy Pathways
- [PINK1](/genes/pink1)/[Parkin](/genes/parkin): Mitophagy initiation mechanisms
- MFN1/2: Mitochondrial fusion dynamics
- Parkinsonism models: Genetic and toxin-based
- Therapeutic targets: Enhancing mitophagy
Energy Metabolism
- Complex I deficiency: Electron transport chain
- CoQ10 approaches: Mitochondrial supplementation
- Metabolic enhancers: ATP production support
Motor and Non-Motor Symptoms
Motor Complications
- Dyskinesia mechanisms: L-DOPA-induced movements
- Continuous delivery: LCIG and pump therapies
- Device-based treatments: Deep brain stimulation
Non-Motor Symptoms
- Sleep disorders: REM sleep behavior disorder
- Cognitive impairment: Dementia in PD
- Autonomic dysfunction: Gastrointestinal issues
Cross-Disease Themes
Common Mechanisms
Protein Aggregation
- Prion-like spread: Common mechanisms across diseases
- Strain variation: Disease-specific aggregates
- Seeding assays: Cross-diagnostic applications
Neuroinflammation
- Microglial activation: Shared pathways
- Complement involvement: Synaptic loss mechanisms
- Peripheral immunity: Systemic-brain connections
Biomarker Convergence
- p-tau in PD: Alzheimer's biomarkers in Parkinson's
- Alpha-synuclein in AD: Lewy body pathology in AD
- NfL:通用 neurodegeneration marker
Awards and Recognitions
Young Investigator Awards
- Best Basic Science Abstract: Protein aggregation mechanisms
- Best Clinical Abstract: Biomarker-driven trial design
- Best Translational Abstract: Therapeutic development
Travel Grants
Supported by:
- Movement Disorder Society
- Alzheimer's Association
- Industry sponsors
Poster Session Highlights
Day 1: Amyloid and Basic Mechanisms
Featured posters on:
- APP processing and trafficking
- Amyloid generation and clearance
- Synaptic dysfunction
Day 2: Tau and Neuroinflammation
Featured posters on:
- Tau post-translational modifications
- Microglial activation states
- [Complement system](/entities/complement-system)
Day 3: Alpha-Synuclein and Genetics
Featured posters on:
- Seed amplification assays
- LRRK2 biology
- GBA-associated PD
Day 4: Biomarkers and Diagnostics
Featured posters on:
- Fluid biomarker development
- PET tracer advancement
- Clinical diagnostics
Day 5: Clinical Trials and Therapeutics
Featured posters on:
- Anti-amyloid trial results
- Anti-tau therapeutic approaches
- Gene and cell therapy
Key Takeaways
See Also
- [AD/PD 2026 Conference](/events/adpd-2026)](/events)
- [AD/PD 2026 Scientific Sessions](/events/adpd-2026-scientific-sessions)](/events)
- [AD/PD 2026 Plenary Sessions](/events/adpd-2026-plenary-sessions)](/events)
- [AD/PD 2026 Clinical Trial Updates](/events/adpd-2026-clinical-trials)](/events)
- [Events Index](/events/conference-index)
References
Related Entities
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| entity_type | event |
| origin_type | v1_polymorphic_backfill |
| source_table | wiki_pages |
| wiki_page_id | wp-87a33eb30192 |
| __merged_from | {'merged_at': '2026-05-13', 'unprefixed_id': 'events-adpd-2026-posters-abstracts'} |
| _schema_version | 1 |
📊 Evidence Profile
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Outgoing
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