POMC

Understanding Entity Pages

This page aggregates everything SciDEX knows about POMC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

POMC is a gene implicated in neurodegeneration research. Key relationships include: expressed in, regulates, activates. Associated with ALS, Aging, Als. Connected to 48 entities in the SciDEX knowledge graph.

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graph TD
    POMC["<b>POMC</b>"]
    Tumor{"Tumor"}
    POMC -->|"expressed in"| Tumor
    Als{"Als"}
    POMC -->|"activates"| Als
    Aging{"Aging"}
    POMC -->|"regulates"| Aging
    Ms{"Ms"}
    POMC -->|"regulates"| Ms
    Obesity{"Obesity"}
    POMC -->|"regulates"| Obesity
    POMC -->|"regulates"| Als
    ALS{"ALS"}
    POMC -->|"activates"| ALS
    POMC -->|"regulates"| ALS
    POMC -->|"activates"| Obesity
    Inflammation{"Inflammation"}
    POMC -->|"activates"| Inflammation
    FOOD_INTAKE["FOOD_INTAKE"]
    POMC -->|"inhibits"| FOOD_INTAKE
    CRHR1["CRHR1"]
    POMC -->|"expressed in"| CRHR1
    ARC["ARC"]
    ARC -->|"produces"| POMC
    CRH["CRH"]
    CRH -->|"expressed in"| POMC
    AVP["AVP"]
    AVP -->|"expressed in"| POMC
    CRH -->|"regulates"| POMC
    CRHR1 -->|"expressed in"| POMC
    NPY["NPY"]
    NPY -->|"regulates"| POMC
    NTS["NTS"]
    NTS -->|"regulates"| POMC
    AND["AND"]
    AND -->|"expressed in"| POMC
    TNF["TNF"]
    TNF -->|"expressed in"| POMC
    AND -->|"regulates"| POMC
    STAT3["STAT3"]
    STAT3 -->|"interacts with"| POMC
    style POMC fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0