protein

ANK2PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ANK2PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Ankyrin B Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	ANK2PROTEIN
Full Name	Ankyrin B
Protein Type	Protein
Function	is an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization	the axon initial segment (AIS), nodes of Ranvier, and the endoplasmic reticulum-plasma membrane interface in neurons, wh
UniProt ID	Search UniProt
GeneCards	ANK2PROTEIN
Human Protein Atlas	ANK2PROTEIN
Ankyrin Alpha	Related membrane adaptor protein with distinct tissue distribution and protein-binding partners
Spectrin	Primary cytoskeletal binding partner of Ankyrin B
Na+/K+-ATPase	Major functional cargo of Ankyrin B
Nodes of Ranvier	Critical neuronal microdomains dependent on Ankyrin B organization
Axon Initial Segment	Primary neuronal compartment requiring Ankyrin B for structural maintenance
Amyloid Precursor Protein	Potential Ankyrin B-interacting protein relevant to Alzheimer's disease pathophysiology
Associated Diseases	neurodegeneration
Interactions	PTEN, COMPLEMENT, IGF2BP1
KG Connections	6 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: ANK2PROTEIN — AlphaFold SEARCH Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Ankyrin B Protein

protein · 658 words

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Pathway Diagram

graph TD
    ANK2PROTEIN["ANK2PROTEIN"]
    neurodegeneration["neurodegeneration"]
    ANK2PROTEIN -->|"implicated_in"| neurodegeneration
    style ANK2PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found