Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about APRIL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Heparan Sulfate Proteoglycans | binds | compound | 0.95 |
| HEPARAN SULFATE PROTEOGLYCANS | binds | protein | 0.95 |
| Atherosclerosis | inhibits | disease | 0.95 |
| Heparan Sulfate Proteoglycans | interacts_with | receptor | 0.92 |
| Atherosclerosis Progression | inhibits | process | 0.90 |
| Heparan Sulfate Proteoglycans | binds_to | protein | 0.90 |
| HSPG2 | binds_to | protein | 0.90 |
| Atherosclerosis | protects_against | disease | 0.90 |
| atherosclerosis | limits | disease | 0.90 |
| atherosclerosis | inhibits | disease | 0.80 |
| Low-Density Lipoproteins | limits_retention | molecule | 0.80 |
| macrophages | limits_accumulation | cell | 0.80 |
| Necrotic Cores | limits_formation | pathological_structure | 0.80 |
| cardiovascular disease | therapeutic_target | disease | 0.75 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||