Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Apremilast: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| PDE4 | inhibits | enzyme | 0.95 |
| Pi3K/Akt Pathway | activates | pathway | 0.95 |
| Aβ-Induced Cytotoxicity | protects_against | phenotype | 0.95 |
| AKT | upregulates | gene | 0.90 |
| PI3K | upregulates | gene | 0.90 |
| Alzheimer'S Disease | therapeutic_target | disease | 0.85 |
| Neuroinflammation | inhibits | process | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||