Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ARACHIDONIC ACID: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | ARACHIDONIC ACID |
Knowledge base pages for this entity
graph TD
ARACHIDONIC_ACID["ARACHIDONIC ACID"]
ARACHIDONIC_ACID -->|"component_of"| Neuronal_Membrane["Neuronal Membrane"]
ARACHIDONIC_ACID -->|"product_of"| Cysteinyl_Leukotrienes["Cysteinyl Leukotrienes"]
ARACHIDONIC_ACID -->|"product_of"| Eicosanoids["Eicosanoids"]
ARACHIDONIC_ACID -->|"involved_in"| Neural_Development["Neural Development"]
ARACHIDONIC_ACID -->|"substrate_of"| Prostaglandin_Biosynthesis["Prostaglandin Biosynthesis"]
ARACHIDONIC_ACID -.protects against.-> Neurodegeneration["Neurodegeneration"]
ARACHIDONIC_ACID -->|"encodes"| Prostaglandins["Prostaglandins"]
ARACHIDONIC_ACID -->|"encodes"| Leukotrienes["Leukotrienes"]
ALOX5["ALOX5"] -->|"catalyzes"| ARACHIDONIC_ACID
ALOX15["ALOX15"] -->|"targets"| ARACHIDONIC_ACID
PLA2["PLA2"] -->|"catalyzes"| ARACHIDONIC_ACID
PLA2G4A["PLA2G4A"] -->|"catalyzes"| ARACHIDONIC_ACID
Phospholipase_A2["Phospholipase A2"] -->|"activates"| ARACHIDONIC_ACID| Target | Relation | Type | Str |
|---|---|---|---|
| Neuronal Membrane | component_of | process | 0.95 |
| Cysteinyl Leukotrienes | product_of | compound | 0.95 |
| Prostaglandin Biosynthesis | involved_in | pathway | 0.95 |
| prostaglandin E2 | mediates | compound | 0.95 |
| prostaglandin F2alpha | mediates | compound | 0.95 |
| Eicosanoids | product_of | compound | 0.90 |
| Neural Development | involved_in | process | 0.90 |
| Prostaglandin Biosynthesis | substrate_of | pathway | 0.90 |
| NEURON | involved_in | cell_type | 0.90 |
| Pro-Inflammatory Eicosanoids | associated_with | compound | 0.85 |
| Neurodegeneration | protects_against | disease | 0.75 |
| Prostaglandins | encodes | drug | 0.70 |
| Leukotrienes | encodes | drug | 0.70 |
| Epoxyeicosatrienoic acid | encodes | drug | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ALOX5 | associated_with | gene | 0.95 |
| PLA2 | catalyzes | enzyme | 0.90 |
| PLA2 | product_of | enzyme | 0.90 |
| PLA2G6 | associated_with | gene | 0.90 |
| Phospholipase A2 | activates | protein | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||