Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about BPA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | BPA |
| Key Genes/Proteins | TP53, AMPK |
| Related Diseases | OVARIAN_DYSFUNCTION |
| Related Pathways | AUTOPHAGY |
Knowledge base pages for this entity
graph TD
BPA["BPA"]
BPA -->|"causes"| Granulosa_Cells["Granulosa Cells"]
BPA -->|"activates"| Ampk_Mtor_Ulk1["Ampk/Mtor/Ulk1"]
BPA -->|"activates"| AMPK["AMPK"]
BPA -->|"downregulates"| Oocyte_Maturation["Oocyte Maturation"]
BPA -->|"inhibits"| Follicle_Development["Follicle Development"]
BPA -->|"causes"| neurotoxicity["neurotoxicity"]
BPA -->|"downregulates"| Estradiol["Estradiol"]
BPA -->|"risk_factor_for"| Infertility["Infertility"]| Target | Relation | Type | Str |
|---|---|---|---|
| neurotoxicity | causes | process | 0.88 |
| TP53 | binds_to | gene | 0.85 |
| AUTOPHAGY | activates | pathway | 0.72 |
| AMPK | activates | protein | 0.64 |
| GRANULOSA_CELLS | causes | cell_type | 0.64 |
| OVARIAN_DYSFUNCTION | causes | phenotype | 0.64 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||