gene 1,769 words KG: CEBPA 2026-03-25
kind:genesection:genesstate:published
Contents

CEBPA Gene

🧬 Gene Info
Gene SymbolCEBPA
Full NameCEBPA
AliasesCCAAT/Enhancer Binding Protein Alpha
Protein TypeGene
Functionencodes a transcription factor belonging to the C/EBP family of basic leucine zipper (bZIP) proteins.
Primary ExpressionBroad tissue distribution; high expression in liver, adipose tissue, and hematopoietic cells; moderate expression in brain (astrocytes, microglia, neu
Molecular Weight42 kDa
PathwaysApoptosis, Cholesterol
UniProt IDP49715
NCBI Gene ID1050
Ensembl IDENSG00000172270
OMIM116897
GeneCardsCEBPA
Human Protein AtlasCEBPA
Associated DiseasesALS, Alzheimer, Multiple Sclerosis, Parkinson
KG Connections137 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.46
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Lysosomal Positioning Dynamics Modulation
Score: 0.43

Related Analyses (6)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived

See Also (11)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: regulates
Packard Center for ALS Research
institution · KG edge: regulates
Alzheimer Indonesia
institution · KG edge: associated_with
CAMK2G — Calcium/Calmodulin-Dependent Kinase 2 Gamma
gene · KG edge: expressed_in
CACNG6 (TARP γ8)
gene · KG edge: associated_with

Knowledge Graph (12 edges)

CEBPA therapeutic_target HSPA1A
CEBPA regulates TFE3
CEBPA regulates TP53
CEBPA regulates SPI1
CEBPA therapeutic_target CNR1
CEBPA associated_with CTSD
CEBPA therapeutic_target NME1
CEBPA associated_with CACNA1E
CEBPA associated_with CACNA2D3
CEBPA therapeutic_target PRKAB1