concept

BRAIN ARTERIOVENOUS MALFORMATIONS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BRAIN ARTERIOVENOUS MALFORMATIONS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

19Connections

0Hypotheses

0Analyses

3Outgoing

8Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	BRAIN ARTERIOVENOUS MALFORMATIONS

Wiki Pages (4)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    BRAIN_ARTERIOVENOUS_MALFORMATI["BRAIN ARTERIOVENOUS MALFORMATIONS"]
    BRAIN_ARTERIOVENOUS_MALFORMATI -->|"downregulates"| CLDN5["CLDN5"]
    BRAIN_ARTERIOVENOUS_MALFORMATI -->|"downregulates"| OCLN["OCLN"]
    BRAIN_ARTERIOVENOUS_MALFORMATI -->|"inhibits"| BLOOD_BRAIN_BARRIER["BLOOD-BRAIN BARRIER"]
    BRAIN_ARTERIOVENOUS_MALFORMATI -->|"causes"| Blood_Brain_Barrier["Blood-Brain Barrier"]
    BRAIN_ARTERIOVENOUS_MALFORMATI -->|"downregulates"| Tight_Junction_Protein_Express["Tight Junction Protein Expression"]
    Blood_Brain_Barrier -->|"involved_in"| BRAIN_ARTERIOVENOUS_MALFORMATI
    CLDN5 -.biomarker for.-> BRAIN_ARTERIOVENOUS_MALFORMATI
    OCLN -.biomarker for.-> BRAIN_ARTERIOVENOUS_MALFORMATI
    Tight_Junction_Proteins["Tight Junction Proteins"] -.biomarker for.-> BRAIN_ARTERIOVENOUS_MALFORMATI
    Tight_Junction_Protein_Express -.biomarker for.-> BRAIN_ARTERIOVENOUS_MALFORMATI

Outgoing (11)

Target	Relation	Type	Str
CLDN5	downregulates	entity	0.95
OCLN	downregulates	entity	0.95
BLOOD-BRAIN BARRIER	inhibits	entity	0.95

Incoming (8)

Source	Relation	Type	Str
Blood-Brain Barrier Disruption	associated_with	process	0.95
CLDN5	biomarker_for	protein	0.90
OCLN	biomarker_for	protein	0.90
Tight Junction Proteins	biomarker_for	protein	0.85
Blood-Brain Barrier	biomarker_for	process	0.85
CLDN5	downregulates	gene	0.80
OCLN	downregulates	gene	0.80
Tight Junction Protein Expression	biomarker_for	biomarker	0.75

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

BRAIN ARTERIOVENOUS MALFORMATIONS

Understanding Entity Pages

Wiki Pages (4)

CLDN5 — Claudin-5

Claudin-5 Protein