protein

CAMK4PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CAMK4PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Camk4 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	CAMK4PROTEIN
Chromosome	2q32.1
Protein Type	Kinase
Function	is an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization	the neuronal nucleus where it phosphorylates transcription factors and chromatin-associated proteins. The CAMK4 gene is
Molecular Weight	52 kDa
GeneCards	CAMK4PROTEIN
Human Protein Atlas	CAMK4PROTEIN
CaMKII	Cytoplasmic-predominant calcium/calmodulin-dependent kinase
CREB	Transcription factor; primary CaMK4 nuclear substrate
Calmodulin	Regulatory protein enabling CaMK4 activation
HDAC4	Histone deacetylase; CaMK4 substrate involved in MEF2 regulation
Amyloid-beta	Pathogenic protein disrupting calcium homeostasis in Alz
Associated Diseases	Cancer, Tumor
Interactions	GENES, ZBTB20, ANK3, ETV6, AND, CANCER
KG Connections	31 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

CaMK4 Protein

protein · 609 words

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Pathway Diagram

graph TD
    CAMK4PROTEIN["CAMK4PROTEIN"]
    neurodegeneration["neurodegeneration"]
    CAMK4PROTEIN -->|"implicated_in"| neurodegeneration
    style CAMK4PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found