Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Cathepsin_D: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Neuronal_Ceroid_Lipofuscinosis | deficiency_causes | mechanism | 0.50 |
| aged_brain | reduced_activity_in | mechanism | 0.50 |
| alpha_synuclein_fibrillization | activates | mechanism | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Lysosomal Cathepsin-Dependent Tau Clearance | 0.767 | neurodegeneration | View |
| Cathepsin D Replacement to Overcome Lysosomal Protease Defic | 0.457 | proteomics | Quantitative proteomics of the aging syn |
| Cathepsin-Dependent Processing of Pro-Drug Enzymes | 0.400 | neurodegeneration | How does controlled lysosomal membrane p |
Scientific analyses that reference this entity
proteomics | 2026-04-16 | 7 hypotheses Top: 0.533
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning Cathepsin_D in their description or question text
No additional research found