gene 2,704 words KG: CATHEPSIND 2026-03-28
kind:genesection:genesstate:published
Contents

CTSD Gene - Cathepsin D

🧬 Gene Info
Gene SymbolCTSD
Full NameCathepsin D
AliasesCPSD, CLN10
Chromosome11p15.5
Protein FamilyAspartyl protease (peptidase A1)
Protein TypeProtease
Functionis a lysosomal aspartic protease encoded by the CTSD gene.
Primary ExpressionBrain, liver, macrophages, neurons, microglia
Subcellular LocalizationLysosome
Molecular Weight52 kDa (prepro), 31 kDa (mature)
Amino Acids412 amino acids
Gene TypeProtein coding
PathwaysAkt, Angiogenesis, Apoptosis, Autophagy, Blood-Brain Barrier
UniProt IDP07339
NCBI Gene ID1509
Ensembl IDENSG00000160336
OMIM116840
GeneCardsCTSD
Human Protein AtlasCTSD
Associated DiseasesAD, ADH, ALI, ALS, AMI, Aging
Known Drugs/CompoundsRAPAMYCIN, COENZYME Q10, rapamycin, CHLOROQUINE
InteractionsRB1, EIF2AK3, PRKN, BCL2L11, MUL1, BNIP3
KG Connections1566 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph