| Gene Symbol | CTSD |
| Full Name | Cathepsin D |
| Aliases | CPSD, CLN10 |
| Chromosome | 11p15.5 |
| Protein Type | Protease |
| Function | is a lysosomal aspartic protease encoded by the CTSD gene. |
| Primary Expression | Brain, liver, macrophages, neurons, microglia |
| Subcellular Localization | mitochondria and trigger caspase-mediated apoptosis under stress conditions. Additionally, cathepsin D regulates express |
| Molecular Weight | 48 kDa |
| Pathways | Akt, Angiogenesis, Apoptosis, Autophagy, Blood-Brain Barrier |
| UniProt ID | P07339 |
| NCBI Gene ID | 1509 |
| Ensembl ID | ENSG00000103811 |
| GeneCards | CTSD |
| Human Protein Atlas | CTSD |
| Associated Diseases | AD, ADH, ALI, ALS, AMI, Aging |
| Known Drugs/Compounds | RAPAMYCIN, COENZYME Q10, rapamycin, CHLOROQUINE |
| Interactions | RB1, EIF2AK3, PRKN, BCL2L11, MUL1, BNIP3 |
| KG Connections | 1566 knowledge graph edges |
| Databases | GeneCardsHPASTRING |