CLASSICAL COMPLEMENT CASCADE

Understanding Entity Pages

This page aggregates everything SciDEX knows about CLASSICAL COMPLEMENT CASCADE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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graph TD
    CLASSICAL_COMPLEMENT_CASCADE["CLASSICAL COMPLEMENT CASCADE"]
    CLASSICAL_COMPLEMENT_CASCADE -->|"causes"| Demyelination["Demyelination"]
    CLASSICAL_COMPLEMENT_CASCADE -->|"causes"| Granulocyte_Infiltration["Granulocyte Infiltration"]
    CLASSICAL_COMPLEMENT_CASCADE -->|"causes"| Eosinophil_Infiltration["Eosinophil Infiltration"]
    CLASSICAL_COMPLEMENT_CASCADE -->|"causes"| Lymphocyte_Infiltration["Lymphocyte Infiltration"]
    CLASSICAL_COMPLEMENT_CASCADE -->|"causes"| Astrocyte_Injury["Astrocyte Injury"]
    CLASSICAL_COMPLEMENT_CASCADE -->|"activates"| leukocyte_infiltration["leukocyte infiltration"]
    Aquaporin_4_IgG["Aquaporin-4-IgG"] -->|"activates"| CLASSICAL_COMPLEMENT_CASCADE
    AQP4_Ab["AQP4-Ab"] -->|"activates"| CLASSICAL_COMPLEMENT_CASCADE
    C1Q["C1Q"] -->|"activates"| CLASSICAL_COMPLEMENT_CASCADE
    Eculizumab["Eculizumab"] -->|"inhibits"| CLASSICAL_COMPLEMENT_CASCADE
    TREM2["TREM2"] -->|"inhibits"| CLASSICAL_COMPLEMENT_CASCADE
    AQP4_ab["AQP4-ab"] -->|"activates"| CLASSICAL_COMPLEMENT_CASCADE
    AQP4_ANTIBODY["AQP4-ANTIBODY"] -->|"activates"| CLASSICAL_COMPLEMENT_CASCADE