C4B

Understanding Entity Pages

This page aggregates everything SciDEX knows about C4B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Complement component C4B gene - role in immune function, neuroinflammation, and connection to neurodegenerative and autoimmune diseases

View on Wiki →

graph TD
    C4B["<b>C4B</b>"]
    Alzheimer{"Alzheimer"}
    C4B -->|"associated with"| Alzheimer
    Ms{"Ms"}
    C4B -->|"expressed in"| Ms
    Schizophrenia{"Schizophrenia"}
    C4B -->|"expressed in"| Schizophrenia
    Als{"Als"}
    C4B -->|"expressed in"| Als
    C4B -->|"associated with"| Als
    Tumor{"Tumor"}
    C4B -->|"regulates"| Tumor
    Inflammation{"Inflammation"}
    C4B -->|"expressed in"| Inflammation
    ALS{"ALS"}
    C4B -->|"expressed in"| ALS
    Complement(["Complement"])
    C4B -->|"expressed in"| Complement
    JUN["JUN"]
    C4B -->|"associated with"| JUN
    TREM2["TREM2"]
    C4B -->|"associated with"| TREM2
    GENES["GENES"]
    C4B -->|"expressed in"| GENES
    JUN -->|"associated with"| C4B
    TREM2 -->|"associated with"| C4B
    C4A["C4A"]
    C4A -->|"expressed in"| C4B
    COMPLEMENT["COMPLEMENT"]
    COMPLEMENT -->|"regulates"| C4B
    CYTOKINES["CYTOKINES"]
    CYTOKINES -->|"activates"| C4B
    TNF["TNF"]
    TNF -->|"expressed in"| C4B
    INFLAMMATION["INFLAMMATION"]
    INFLAMMATION -->|"expressed in"| C4B
    IL_6["IL-6"]
    IL_6 -->|"activates"| C4B
    DISEASE_ASSOCIATED_MICROGLIA["DISEASE-ASSOCIATED MICROGLIA"]
    DISEASE_ASSOCIATED_MICROGLIA -->|"associated with"| C4B
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"associated with"| C4B
    MICROGLIA["MICROGLIA"]
    MICROGLIA -->|"associated with"| C4B
    ALZHEIMER["ALZHEIMER"]
    ALZHEIMER -->|"associated with"| C4B
    style C4B fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0