protein

DARS2PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DARS2PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🔬 Protein Info

Gene Symbol	DARS2PROTEIN
Full Name	Mitochondrial Aspartyl-tRNA Synthetase
Protein Family	Aminoacyl-tRNA synthetases, class II
Protein Type	Enzyme
Function	is an essential enzyme that catalyzes the attachment of aspartic acid to its cognate tRNA in mitochondria.
Primary Expression	High in brain, heart, muscle
Molecular Weight	~80 kDa (645 amino acids)
Amino Acids	645 aa
UniProt ID	Q9N1W8
NCBI Gene ID	27165
GeneCards	DARS2PROTEIN
Human Protein Atlas	DARS2PROTEIN
Associated Diseases	neurodegeneration
Interactions	CDK4, ERK, MYC, PINK1
KG Connections	11 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: DARS2PROTEIN — AlphaFold Q9N1W8 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Mitochondrial Aspartyl-tRNA Synthetase

protein · 1180 words

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Pathway Diagram

graph TD
    DARS2PROTEIN["DARS2PROTEIN"]
    neurodegeneration["neurodegeneration"]
    DARS2PROTEIN -->|"implicated_in"| neurodegeneration
    style DARS2PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning DARS2PROTEIN in their description or question text

No additional research found