CDK4

Understanding Entity Pages

This page aggregates everything SciDEX knows about CDK4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CDK4 is a gene implicated in neurodegeneration research. Key relationships include: associated with, activates, therapeutic target. Associated with Als, Autism, Breast Cancer. Connected to 264 entities in the SciDEX knowledge graph.

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graph TD
    CDK4["CDK4"]
    CDK4 -->|"interacts"| RB1["RB1"]
    CDK4 -->|"activates"| Cancer["Cancer"]
    CDK4 -->|"activates"| Als["Als"]
    CDK4 -->|"activates"| Senescence["Senescence"]
    CDK4 -->|"activates"| Inflammation["Inflammation"]
    CDK4 -->|"activates"| Tumor["Tumor"]
    CDK4 -->|"regulates"| Ms["Ms"]
    RANK["RANK"] -->|"activates"| CDK4
    RANKL["RANKL"] -->|"activates"| CDK4
    FGFR1["FGFR1"] -->|"target for"| CDK4
    SOX2["SOX2"] -->|"target for"| CDK4
    MYC["MYC"] -->|"regulates"| CDK4
    EBF3["EBF3"] -->|"regulates"| CDK4
    RB1 -->|"regulates"| CDK4
    GBM["GBM"] -->|"regulates"| CDK4