concept

GJA1-20K

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GJA1-20K: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

28Connections

0Hypotheses

0Analyses

4Outgoing

2Incoming

0Experiments

No summary available yet. View on Wiki →

💡 Concept Info

Name	GJA1-20K
Key Genes/Proteins	CONNEXIN 43

Wiki Pages (1)

Knowledge base pages for this entity

Mitochondrial Dynamics

entity · 2310 words

→

Pathway Diagram

graph TD
    GJA1_20K["GJA1-20K"]
    GJA1_20K -->|"involved_in"| Gap_Junction_Formation["Gap Junction Formation"]
    GJA1_20K -->|"interacts"| Connexin_43["Connexin 43"]
    GJA1_20K -->|"activates"| Mitochondrial_Fission["Mitochondrial Fission"]
    GJA1_20K -.protects against.-> Ischemic_Injury["Ischemic Injury"]
    GJA1_20K -->|"involved_in"| Mitochondrial_Transfer["Mitochondrial Transfer"]
    GJA1_20K -->|"downregulates"| Reactive_Oxygen_Species["Reactive Oxygen Species"]
    GJA1_20K -->|"upregulates"| ATP_Production["ATP Production"]
    GJA1_20K -->|"involved_in"| Mitochondrial_Dynamics["Mitochondrial Dynamics"]
    Ischemic_Preconditioning["Ischemic Preconditioning"] -->|"upregulates"| GJA1_20K
    Metabolic_Stress["Metabolic Stress"] -->|"upregulates"| GJA1_20K
    Ischemic_Stress["Ischemic Stress"] -->|"upregulates"| GJA1_20K

Outgoing (22)

Target	Relation	Type	Str
Gap Junction Formation	associated_with	process	0.90
Mitochondrial Dynamics	involved_in	process	0.85
CONNEXIN 43	interacts_with	protein	0.85
mitochondrial dynamics	regulates	process	0.80

Incoming (6)

Source	Relation	Type	Str
Metabolic Stress	upregulates	process	0.80
Ischemic Stress	upregulates	process	0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found