REACTIVE OXYGEN SPECIES

Understanding Entity Pages

This page aggregates everything SciDEX knows about REACTIVE OXYGEN SPECIES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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graph TD
    REACTIVE_OXYGEN_SPECIES["REACTIVE OXYGEN SPECIES"]
    REACTIVE_OXYGEN_SPECIES -->|"modulates"| DUBS["DUBS"]
    REACTIVE_OXYGEN_SPECIES -->|"modulates"| DUB["DUB"]
    REACTIVE_OXYGEN_SPECIES -->|"involved_in"| Neutrophil_Extracellular_Traps["Neutrophil Extracellular Traps"]
    REACTIVE_OXYGEN_SPECIES -.biomarker for.-> Hypertrophic_Scar["Hypertrophic Scar"]
    REACTIVE_OXYGEN_SPECIES -->|"modulates"| Catalytic_Cysteine["Catalytic Cysteine"]
    REACTIVE_OXYGEN_SPECIES -->|"contributes to"| amyloid_beta["amyloid beta"]
    REACTIVE_OXYGEN_SPECIES -->|"activates"| Separating_Microneedles["Separating Microneedles"]
    REACTIVE_OXYGEN_SPECIES -->|"contributes to"| Learning_and_Memory_Deficits["Learning and Memory Deficits"]
    REACTIVE_OXYGEN_SPECIES -->|"contributes to"| Protein_Accumulation["Protein Accumulation"]
    REACTIVE_OXYGEN_SPECIES -->|"activates"| mitochondrial_dysfunction["mitochondrial dysfunction"]
    HSPA1A["HSPA1A"] -->|"inhibits"| REACTIVE_OXYGEN_SPECIES
    Antioxidants["Antioxidants"] -->|"downregulates"| REACTIVE_OXYGEN_SPECIES
    PGC1A["PGC1A"] -->|"regulates"| REACTIVE_OXYGEN_SPECIES
    SLC7A11["SLC7A11"] -->|"downregulates"| REACTIVE_OXYGEN_SPECIES
    MT1["MT1"] -->|"modulates"| REACTIVE_OXYGEN_SPECIES
    MT2["MT2"] -->|"modulates"| REACTIVE_OXYGEN_SPECIES
    Dolutegravir["Dolutegravir"] -->|"upregulates"| REACTIVE_OXYGEN_SPECIES
    Lactic_Acid["Lactic Acid"] -->|"downregulates"| REACTIVE_OXYGEN_SPECIES
    GJA1_20k["GJA1-20k"] -->|"downregulates"| REACTIVE_OXYGEN_SPECIES
    Mitophagic_Flux_Inhibition["Mitophagic Flux Inhibition"] -->|"causes"| REACTIVE_OXYGEN_SPECIES