Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HML-2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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graph TD
HML_2["HML-2"]
HML_2 -->|"inhibits"| ASRGL1["ASRGL1"]
HML_2 -->|"contributes to"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
HML_2 -->|"causes"| Neuron["Neuron"]
HML_2 -->|"causes"| RNA["RNA"]
HML_2 -->|"causes"| DNA["DNA"]
HML_2 -->|"contributes to"| Rb["Rb"]
HML_2 -->|"expressed in"| Cortex["Cortex"]
RNA -->|"causes"| HML_2
DNA -->|"causes"| HML_2
AMYOTROPHIC_LATERAL_SCLEROSIS["AMYOTROPHIC LATERAL SCLEROSIS"] -->|"causes"| HML_2| Target | Relation | Type | Str |
|---|---|---|---|
| ASRGL1 | inhibits | gene | 0.85 |
| Amyotrophic Lateral Sclerosis | contributes_to | disease | 0.80 |
| Amyotrophic Lateral Sclerosis | causes | disease | 0.65 |
| Als | associated_with | disease | 0.65 |
| ASRGL1 | associated_with | gene | 0.60 |
| Neuron | causes | cell_type | 0.60 |
| RNA | causes | gene | 0.60 |
| Rb | contributes_to | protein | 0.60 |
| Tdp-43 | associated_with | pathway | 0.60 |
| AND | associated_with | gene | 0.60 |
| ALS | associated_with | gene | 0.60 |
| DNA | causes | gene | 0.60 |
| Cortex | expressed_in | brain_region | 0.55 |
| Neuron | expressed_in | cell_type | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity