Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HNRNPM: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | HNRNPM |
| Chromosome | 19p13.3 |
| Function | RNA Recognition Motifs (RRMs): Four RRMs (RRM1-4) in the central region enable sequence-specific RNA binding. |
| Primary Expression | all tissues examined - Highest expression in brain, heart, and skeletal muscle - In the brain, localized to neurons throughout cortex, hippocampus, an |
| Subcellular Localization | neurons throughout cortex, hippocampus, and cerebellum |
| Molecular Weight | 77 kDa |
| Amino Acids | 730 aa |
| Ensembl ID | ENSG00000177868 |
| GeneCards | HNRNPM |
| Human Protein Atlas | HNRNPM |
| Associated Diseases | neurodegeneration |
| Interactions | CANCER, RBFOX2 |
| KG Connections | 6 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
HNRNPM["<b>HNRNPM</b>"]
Cancer{"Cancer"}
HNRNPM -->|"interacts with"| Cancer
Tumor{"Tumor"}
HNRNPM -->|"regulates"| Tumor
neurodegeneration["neurodegeneration"]
HNRNPM -->|"implicated in"| neurodegeneration
RBFOX2["RBFOX2"]
RBFOX2 -->|"interacts with"| HNRNPM
RAC1["RAC1"]
RAC1 -->|"expressed in"| HNRNPM
MYC["MYC"]
MYC -->|"regulates"| HNRNPM
CANCER["CANCER"]
CANCER -->|"interacts with"| HNRNPM
style HNRNPM fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity