Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KIF5BPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
KIF5B is encoded by the KIF5B gene located on chromosome 10p11.21 in humans[@navone1992]. The protein is composed of 1047 amino acids with a molecular weight of approximately 110 kDa[@aizawa1992].
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| Gene Symbol | KIF5BPROTEIN |
| Full Name | Kinesin-1 Heavy Chain |
| Chromosome | 10p11.21 |
| Protein Type | Protein |
| Function | is a member of the kinesin-1 family, which is responsible for the long-range transport of organelles, protein complexes, and signaling molecules throughout the cytoplasm[@vale1992]. |
| Molecular Weight | 110 kDa |
| Amino Acids | 1047 aa |
| UniProt ID | Search UniProt |
| GeneCards | KIF5BPROTEIN |
| Human Protein Atlas | KIF5BPROTEIN |
| Associated Diseases | ALS, neurodegeneration |
| Interactions | ALS, AMYOTROPHIC LATERAL SCLEROSIS, AND, APOPTOSIS, ASTROCYTES, AURKB |
| KG Connections | 115 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
KIF5BPROTEIN["KIF5BPROTEIN"]
neurodegeneration["neurodegeneration"]
KIF5BPROTEIN -->|"implicated_in"| neurodegeneration
style KIF5BPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning KIF5BPROTEIN in their description or question text
No additional research found