Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NAD METABOLISM: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NAD METABOLISM |
Knowledge base pages for this entity
graph TD
NAD_METABOLISM["NAD METABOLISM"]
NAD_METABOLISM -->|"regulates"| Inflammatory_Response["Inflammatory Response"]
NAD_METABOLISM -->|"mediates"| Inflammatory_Pathways["Inflammatory Pathways"]
NAD_METABOLISM -->|"interacts"| Transcriptional_Pathways["Transcriptional Pathways"]
NAD_METABOLISM -->|"participates in"| Excitotoxicity["Excitotoxicity"]
NAD_METABOLISM -->|"interacts"| inflammation["inflammation"]
NAD_METABOLISM -->|"interacts"| senescence["senescence"]
NAMPT["NAMPT"] -->|"catalyzes"| NAD_METABOLISM
NAD_DEPLETING_ENZYMES["NAD-DEPLETING ENZYMES"] -->|"modulates"| NAD_METABOLISM| Target | Relation | Type | Str |
|---|---|---|---|
| intestinal inflammation | drives | phenotype | 0.90 |
| Inflammatory Response | regulates | process | 0.85 |
| Inflammatory Pathways | mediates | pathway | 0.85 |
| Inflammatory Pathways | interacts_with | pathway | 0.80 |
| Transcriptional Pathways | interacts_with | pathway | 0.80 |
| Excitotoxicity | participates_in | mechanism | 0.80 |
| IBD | associated_with | disease | 0.80 |
| cancer | associated_with | disease | 0.70 |
| neurodegeneration | associated_with | disease | 0.70 |
| aging | associated_with | process | 0.70 |
| inflammation | interacts_with | process | 0.70 |
| senescence | interacts_with | process | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| NAD-DEPLETING ENZYMES | modulates | enzyme | 0.85 |
| PARP1 | involved_in | gene | 0.80 |
| SIRT6 | involved_in | gene | 0.80 |
| CD38 | involved_in | gene | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||