Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about P2X7R: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Microglia | expressed_in | cell_type | 0.95 |
| Alzheimer'S Disease | upregulates | disease | 0.90 |
| Caspase-1 | activates | protein | 0.85 |
| NLRP3 Inflammasome | activates | pathway | 0.85 |
| Neurodegeneration | involved_in | process | 0.85 |
| NLRP3 | interacts_with | protein | 0.80 |
| NLRP3 | modulates | protein | 0.80 |
| NLRP3 | activates | protein | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Brilliant Blue G | inhibits | drug | 0.90 |
| ADK | upstream_of | protein | 0.80 |
| Ketogenic Diet | inhibits | drug | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||