entity

PDCD1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PDCD1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections

0Hypotheses

0Analyses

10Outgoing

6Incoming

Wiki Pages (1)

Knowledge base pages for this entity

PD-1/PD-L1 Immune Checkpoint Signaling in Neurodegeneration

mechanism · 3120 words

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Outgoing (10)

Target	Relation	Type	Str
CD8+ T cell exhaustion	regulates	process	0.95
Immune Homeostasis	regulates	process	0.90
T Cell Exhaustion	causes	phenotype	0.90
T_PEX cell	expressed_in	cell_type	0.90
immune homeostasis	involved_in	process	0.90
antitumor immunity	inhibits	process	0.88
CD8+ T Cell	expressed_in	cell_type	0.85
T cell exhaustion	promotes	phenotype	0.85
ILC1	expressed_in	cell_type	0.80
macrophages	expressed_in	cell_type	0.55

Incoming (6)

Source	Relation	Type	Str
CD274	binds	gene	0.95
Nivolumab	targets	drug	0.90
Pembrolizumab	targets	drug	0.90
B7S1	co_expressed_with	protein	0.80
IL1B	interacts_with	gene	0.60
HLA	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found