PDHX

Understanding Entity Pages

This page aggregates everything SciDEX knows about PDHX: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PDHX - Pyruvate Dehydrogenase Complex Component X - critical E3-binding protein in energy metabolism with links to Leigh syndrome and neurodegenerative diseases

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flowchart TD
    N0["PDHX"]
    N1["Als"]
    N0 -->|"associated with"| N1
    N2["ALS"]
    N0 -->|"associated with"| N2
    N3["SLC16A2"]
    N0 -->|"associated with"| N3
    N4["GNAO1"]
    N0 -->|"associated with"| N4
    N5["SATB2"]
    N0 -->|"associated with"| N5
    N6["SPAST"]
    N0 -->|"associated with"| N6
    N7["AND"]
    N0 -->|"associated with"| N7
    N8["ATL1"]
    N0 -->|"associated with"| N8
    N9["Rb"]
    N0 -->|"associated with"| N9
    N6 -->|"associated with"| N0
    N10["COL4A1"]
    N10 -->|"associated with"| N0
    N5 -->|"associated with"| N0
    N8 -->|"associated with"| N0
    N11["GENES"]
    N11 -->|"associated with"| N0

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 disease
    class N2 disease
    class N3 gene
    class N4 gene
    class N5 gene
    class N6 gene
    class N7 gene
    class N8 gene
    class N9 protein
    class N10 gene
    class N11 gene