Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PDIA3PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
ERP57 is a protein involved in protein folding and ER homeostasis.<sup>[1]</sup> This protein plays important roles in the endoplasmic reticulum where it assists in protein folding and quality control.
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| Gene Symbol | PDIA3PROTEIN |
| Protein Type | Chaperone |
| Function | is a protein involved in protein folding and ER homeostasis. |
| Molecular Weight | 57 kDa |
| GeneCards | PDIA3PROTEIN |
| Human Protein Atlas | PDIA3PROTEIN |
| Associated Diseases | neurodegeneration |
| Interactions | AND, CLOCK, C-MYC, DNA, ERP57, MYC |
| KG Connections | 33 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
PDIA3PROTEIN["PDIA3PROTEIN"]
neurodegeneration["neurodegeneration"]
PDIA3PROTEIN -->|"implicated_in"| neurodegeneration
style PDIA3PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity