CLOCK

Understanding Entity Pages

This page aggregates everything SciDEX knows about CLOCK: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CLOCK is a gene implicated in neurodegeneration research. Key relationships include: activates, regulates, associated with. Associated with ALS, Aging, Als. Connected to 641 entities in the SciDEX knowledge graph.

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flowchart TD
    CLOCK(["CLOCK"])
    Cancer["Cancer"]
    Aging["Aging"]
    AGING(["AGING"])
    Als["Als"]
    METABOLIC_HEALTH["METABOLIC HEALTH"]
    autophagy["autophagy"]
    mitophagy["mitophagy"]
    mitochondrial_autophagy["mitochondrial autophagy"]
    cell_survival("cell survival")
    BMAL1(["BMAL1"])
    Period_genes(["Period genes"])
    Cryptochrome_genes(["Cryptochrome genes"])
    Circadian_Rhythms("Circadian Rhythms")
    Cellular_Metabolism("Cellular Metabolism")

    CLOCK -->|"associated with"| Cancer
    CLOCK -->|"associated with"| Aging
    CLOCK -->|"associated with"| AGING
    CLOCK -->|"activates"| Als
    CLOCK -->|"associated with"| Als
    CLOCK -->|"regulates"| METABOLIC_HEALTH
    CLOCK -->|"regulates"| autophagy
    CLOCK -->|"regulates"| mitophagy
    CLOCK -->|"regulates"| mitochondrial_autophagy
    CLOCK -->|"regulates"| cell_survival
    CLOCK -->|"interacts with"| BMAL1
    CLOCK -->|"activates"| Period_genes
    CLOCK -->|"activates"| Cryptochrome_genes
    CLOCK -->|"involved in"| Circadian_Rhythms
    CLOCK -->|"regulates"| Cellular_Metabolism

    style CLOCK fill:#006494,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0