Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PI3K-Akt Pathway: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| GABARAPL1 | downregulates | gene | 0.88 |
| Source | Relation | Type | Str |
|---|---|---|---|
| LARS2 | modulates | gene | 0.85 |
| Andrographis paniculata | inhibits | drug | 0.80 |
| PIEZO1 | activates | protein | 0.80 |
| ASTROCYTE | regulates | cell_type | 0.70 |
| ASTROCYTES | regulates | cell_type | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||