LARS2

Understanding Entity Pages

This page aggregates everything SciDEX knows about LARS2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

LARS2 is a gene implicated in neurodegeneration research. Key relationships include: associated with, activates, inhibits. Associated with Ataxia, Ms. Connected to 28 entities in the SciDEX knowledge graph.

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graph TD
    LARS2["<b>LARS2</b>"]
    Ms{"Ms"}
    LARS2 -->|"activates"| Ms
    LARS2 -->|"associated with"| Ms
    Ataxia{"Ataxia"}
    LARS2 -->|"associated with"| Ataxia
    MFN2["MFN2"]
    LARS2 -->|"inhibits"| MFN2
    RUNX2["RUNX2"]
    LARS2 -->|"activates"| RUNX2
    PIEZO1["PIEZO1"]
    LARS2 -->|"activates"| PIEZO1
    Mitochondrial_Function(["Mitochondrial Function"])
    LARS2 -->|"activates"| Mitochondrial_Function
    POLG["POLG"]
    LARS2 -->|"associated with"| POLG
    SIL1["SIL1"]
    LARS2 -->|"associated with"| SIL1
    STUB1["STUB1"]
    LARS2 -->|"associated with"| STUB1
    FMR1["FMR1"]
    LARS2 -->|"associated with"| FMR1
    TWNK["TWNK"]
    LARS2 -->|"associated with"| TWNK
    DRP1["DRP1"]
    DRP1 -->|"inhibits"| LARS2
    MFN1["MFN1"]
    MFN1 -->|"inhibits"| LARS2
    OPA1["OPA1"]
    OPA1 -->|"inhibits"| LARS2
    WFS1["WFS1"]
    WFS1 -->|"associated with"| LARS2
    HARS["HARS"]
    HARS -->|"associated with"| LARS2
    ATM["ATM"]
    ATM -->|"associated with"| LARS2
    CLPP["CLPP"]
    CLPP -->|"associated with"| LARS2
    SETX["SETX"]
    SETX -->|"associated with"| LARS2
    style LARS2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0