PIK3R2

Understanding Entity Pages

This page aggregates everything SciDEX knows about PIK3R2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PI3K regulatory subunit beta gene involved in Akt signaling and neuronal survival

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flowchart TD
    PIK3R2(["PIK3R2"])
    Thymic_Epithelial_Tumors["Thymic Epithelial Tumors"]
    EphA2(["EphA2"])
    Als["Als"]
    PIK3CA(["PIK3CA"])
    AKT(["AKT"])
    AKT3(["AKT3"])
    PI3K(["PI3K"])
    neurodegeneration["neurodegeneration"]

    PIK3R2 -->|"associated with"| Thymic_Epithelial_Tumors
    PIK3R2 -->|"phosphorylates"| EphA2
    PIK3R2 -->|"associated with"| Als
    PIK3R2 -->|"associated with"| PIK3CA
    PIK3R2 -->|"associated with"| AKT
    PIK3R2 -->|"associated with"| AKT3
    PI3K -->|"associated with"| PIK3R2
    PIK3R2 -->|"implicated in"| neurodegeneration

    style PIK3R2 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff