Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PLCB1PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Plc Beta 1 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
No AI portrait yet
| Gene Symbol | PLCB1PROTEIN |
| Full Name | Phospholipase C Beta 1 |
| Protein Type | Enzyme |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Brain (highest), heart, pancreas |
| Molecular Weight | 155 kDa |
| Amino Acids | 1306 aa |
| UniProt ID | Q14843 |
| GeneCards | PLCB1PROTEIN |
| Human Protein Atlas | PLCB1PROTEIN |
| Associated Diseases | Als, Alzheimer |
| Known Drugs/Compounds | aducanumab |
| Interactions | CAPZB, CD81, GDI2, NDUFA4, NDUFS7, Proteins |
| KG Connections | 45 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
PLCB1PROTEIN["PLCB1PROTEIN"]
neurodegeneration["neurodegeneration"]
PLCB1PROTEIN -->|"implicated_in"| neurodegeneration
style PLCB1PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PLCB1PROTEIN in their description or question text
No additional research found