Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PPARΓ: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| LIPID OXIDATION | regulates | entity | 0.85 |
| THERMOGENESIS | regulates | entity | 0.85 |
| lipid_droplet_biogenesis | regulates | pathway | 0.80 |
| hematoma resolution | mediates | process | 0.80 |
| glucose metabolism | regulates | process | 0.70 |
| fatty acid oxidation | regulates | process | 0.70 |
| PPARGC1A | activates | gene | 0.70 |
| microglial M1 polarization | inhibits | process | 0.70 |
| Parkinson's disease | treats | disease | 0.70 |
| Alzheimer's disease | treats | disease | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| TUG CLEAVAGE PRODUCT | binds_to | entity | 0.90 |
| CX3CR1 | modulates | protein | 0.85 |
| AMPK | activates | protein | 0.80 |
| Tug C-Terminal Cleavage Product | binds | protein | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-01 | 0 hypotheses
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning PPARΓ in their description or question text
No additional research found